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Bovine meat and milk protein in tumor‐free mucosa of colorectal cancer patients

febs.onlinelibrary.wiley.com

1–10 of 36 posts

Re: Bovine meat and milk protein in tumor‐free mucosa of colorectal cancer patients

#2
> BMMFs have been proposed as zoonotic infectious agents and drivers of indirect carcinogenesis of CRC, inducing chronic tissue inflammation, radical formation and increased levels of DNA damage.

There's also a strong relationship between BMMFs and Osteoporosis, which also is linked with hearing loss.

Re: Bovine meat and milk protein in tumor‐free mucosa of colorectal cancer patients

#5

wow...this can def. explain the uptick in colon cancer, especially in young people.

Well it looks a bit weird to me. Maybe due to increased consumption of beef, surely, but not sure if milk consumption has gone up

Though I'm very surprised at the mechanism, that was totally news to me

Re: Bovine meat and milk protein in tumor‐free mucosa of colorectal cancer patients

#7
Does this square epidemiologically with beef consumption? The countries with the highest beef consumption are in South America (and it's sharply more beef consumption); the countries with the highest colon cancer rates are in central and northern Europe.

It doesn't follow from a correlation that beef is by itself causative; it can be, for instance, beef plus some other X-factor. Somebody is going to point out that South American cattle are grass fed, but European cattle are also more grass fed than American cattle, and yet they still top the leaderboard.

Re: Bovine meat and milk protein in tumor‐free mucosa of colorectal cancer patients

#8
So if I understand right, we know that those with colorectal cancer have suspiciously correlated proteins, which could be used for a better screen for this cancer.

But do we know that consuming cow always causes this cancer?

If not, what's next?

Re: Bovine meat and milk protein in tumor‐free mucosa of colorectal cancer patients

#9
From an uninformed intuitive perspective, it would make sense that a substance developed to provide nutrients to rapidly growing babies could cause abnormal growth (tumors) in mature individuals. Same logic applies to artificial growth hormones, which are applied to livestock.

Re: Bovine meat and milk protein in tumor‐free mucosa of colorectal cancer patients

#10
post #7

Does this square epidemiologically with beef consumption? The countries with the highest beef consumption are in South America (and it's sharply more beef consumption); the countries with the highest colon cancer rates are in central and northern Europe. It doesn't follow from a correlation that beef is by itself causative; it can be, for instance, beef plus some other X-factor. Somebody is going to point out that So…

Heavy use of antibiotics?

Edit: perhaps not

> It is estimated that livestock alone uses 50-80% of the total antibiotics produced in most of the developed countries. China, Brazil, and the United States are the largest consumers of antimicrobials in livestock production.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896880/ (Antimicrobial uses for livestock production in developing countries)

An alternative approach would be to sequence the DNA of those who have had this cancer to see if they have a predisposition to this cancer on certain diets due to a specific set of genes.

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