Live data from Hacker News

Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

independent.co.uk

61–70 of 301 posts

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#61

The obese are mad at the diabetics, the diabetics are mad at the obese, while they should be mad at their failure of politicians who won’t regulate the drug market like any other functioning democracy. It’d be funny if it wasn’t so tragic

They should be mad at themselves for failing to take ownership over their own lives and health. But no, its someone elses fault that they eat an entire box of oreos every night.

[dead]

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#62

The obese are mad at the diabetics, the diabetics are mad at the obese, while they should be mad at their failure of politicians who won’t regulate the drug market like any other functioning democracy. It’d be funny if it wasn’t so tragic

[flagged]

[dead]

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#63

> When someone takes an anti-obesity medication like Mounjaro, the amount of fat the body wants to maintain is re-regulated, usually to a lower weight. “When you take the medication away, that defended fat mass goes back up, and weight is regained,” Jastreboff said. “In order to continue to maintain the new re-regulated defended fat mass, and weight reduction, you have to continue taking the medication.” This doesn’t…

It is tough, but that initial "whoosh" can be the momentum someone needs to help them continue/maintain healthy habits they built during that time. I was put on Ozempic last year for a short amount of time. That, combined with changing of diet and starting an exercise routine, lead me to lose ~60 pounds in a relatively short amount of time (~8 months). I'm not taking the medication anymore and I did gain about 20 pou…

It may be a cynical take but I highly doubt most people searching for this drug are going to do what you have done. Props to you for sure but I fear this will just create another cycle of dependence that only benefits the company manufacturing the drug.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#64

https://astralcodexten.substack.com/p/semaglutidonomics These new weight loss medications are the solution to obesity. Imo this is one of the biggest medical advances of the century and at least in urban areas of wealthy countries, I don’t think we’ll see obese people anymore in 10 years. The pharma companies realized they’ve got something truly revolutionary so they took the old tried and true drug dealer strategy.…

Are they the solution to obesity? I'm curious as to whether the weight stays off long term. 10 or more years at least or else it's just another bandaid. What we need is better access to nutritious food that doesn't take up so much of folk's scant downtime and tight income. I understand there's lots of reasons people are obese that aren't just laziness, but the drug doesn't solve those either. They're still not getting the nutrition they need. It's an improvement having poor nutrition with a lower BMI rather than poor nutrition and their current BMI, but not any kind of solution in my opinion.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#65

> When someone takes an anti-obesity medication like Mounjaro, the amount of fat the body wants to maintain is re-regulated, usually to a lower weight. “When you take the medication away, that defended fat mass goes back up, and weight is regained,” Jastreboff said. “In order to continue to maintain the new re-regulated defended fat mass, and weight reduction, you have to continue taking the medication.” This doesn’t…

The biggest problem using these drugs for weight loss is they need to be used as part of a program that also includes making lifestyle changes. If you don't push the changes and just do things to your limits, when you stop the drug, your unchanged habits make you gain the weight back.

This is one of the biggest things people with obesity struggle with. This is seen as a miracle cure for obesity because it doesn't require work, just a weekly injection and watch the weight melt off. But making lifestyle changes (changing eating habits, increasing activity, etc) is the most reliable way to make this a permanent fix.

But that's putting the patient to work and they don't want that.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#66
post #17

The obese are mad at the diabetics, the diabetics are mad at the obese, while they should be mad at their failure of politicians who won’t regulate the drug market like any other functioning democracy. It’d be funny if it wasn’t so tragic

> who won’t regulate the drug market And the food industry, the real root cause of all of this

Ah you’re only scratching the surface. It’s really the “big fork” doing all of the damage.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#67
post #35
post #17

Earlier quoted context omitted.

> who won’t regulate the drug market And the food industry, the real root cause of all of this

Saying food is the cause of obesity is boiling down the visible aggregate effect of a million different things into one big cause. I eat pretty much nothing but garbage food -- pizza, wings, burgers, subs: just salt and grease. And I went from 220 to 120 and stayed there doing it. It's a meme at this point that when we go to restaurants with friends it's the skinny people ordering apps and burgers and the overweight…

The problem is that we're not talking about well educated adults making a conscious decision about eating shit food and ruining their lives. We're talking about entire generations of kids who don't know better being purposefully fed addictive food which will ruin their health.

> I eat pretty much nothing but garbage food -- pizza, wings, burgers, subs: just salt and grease. And I went from 220 to 120 and stayed there doing it

Fast forward 10 years later and you'll get a very concerning blood work result. (I don't wish it on you but the web is full of "fat/skinny/I only eat junk food and I was healthy until I hit 45 and discovered XYZ is 5 times over the recommended limit" stories)

Also you might have a damaged thyroid or other similar health issues, I know a few people coming from an industrial region known for pollution, they have more thyroid issues than the average, as a result they can eat 6+ times a day and much more calories than you'd expect while not packing a gram of fat.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#69

Pro tip, you can lose weight for free with no drugs at all.

I agree with you regarding the general population.

I also hope we can agree that not everyone attains meaningful weight loss with just diet and exercise. The human body is incredibly complex, with a spectrum of natural compositions, metabolisms, etc. Your post dismissing these nuances risks being interpreted as “thin privilege” (my wife is a Dietitian and taught me the concept).

For what it’s worth, I’m against treating drugs like this as a first line of defense against obesity; it should be seen as the last step before bariatric surgery, and only used under the direction of a competent and ethical health professional.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#70
post #36

Mounjaro is not an obesity drug. It's a type 2 diabetes drug. Do not call it an obesity drug. The headline is editorialized. The linked article's headline: The ‘next Ozempic’ became a social media sensation. Then everything changed The coupon didn't go away. The coupon's terms changed. I'm using the coupon now. Because I have type 2 diabetes. The coupon changed because people were using it to get the drug for off-lab…

People aren’t stupid. Mounjaro is the most effective weight loss drug in existence. Better than wegovy and the other brand name semaglutides. If you think FDA approval is going to stop people from wanting and getting it you’re sorely mistaken.

Yeah, feel free to spend the $1200/mo for it then. Because that's off-label use when there are drugs in this class with on-label weight loss use. And sometime this year, tirzepatide is expected to be among them.

The coupon was changed because people were abusing it. This drug is approved for diabetes, not weight loss.

Post reply on HN