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Intermittent fasting associated with increased risk of early death

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Re: Intermittent fasting associated with increased risk of early death

#21

“Among participant with three meals per day, a meal interval of ≤4.5 hours in two adjacent meals was associated with higher all-cause mortality.” So people who ate three meals a day ALSO fared poorly? Am I reading that right?

Eating three meals with a shorter meal interval has higher all-cause mortality than eating three meals with a longer meal interval.

It's not saying anything about 3 meals vs. any other number of meals.

Re: Intermittent fasting associated with increased risk of early death

#22

Maybe because those who are trying to diet are already obese?

A lot of people doing intermittent fasting are not obese. In fact a large portion of the people I know who do it are more athlete/biohacker types (I fall into this bucket myself)

Re: Intermittent fasting associated with increased risk of early death

#24

Maybe because those who are trying to diet are already obese?

I don't think intermittent fasting is 'weight loss dieting'

In my limited personal experience, it's not obese people i see doing intermittent fasting - it's more like the keto crowd.

Re: Intermittent fasting associated with increased risk of early death

#27
post #6

Earlier, on HN I read that it improves lifespan and now it is associated with early death.

Not the same thing... Also there can't be scientific evidence that anything improves lifespan.

Of course there can be evidence.

Re: Intermittent fasting associated with increased risk of early death

#28

Maybe because those who are trying to diet are already obese?

Rather unfortunately, the paper is behind a paywall but the results use this phrase:

  the multivariable-adjusted HRs for participants
That suggests to me that they controlled for BMI or other proxies for obesity.

Re: Intermittent fasting associated with increased risk of early death

#29
post #11

Likely this is because people who are dieting are overweight. This is looking at damaged people and then drawing a conclusion. Pretty good chance these people would have died similar deaths regardless of diet. Better study would compare them to a control group to determine if risk went down or if life expectancy went up.

This is the elephant in the room with MUCH of the healthcare system. They report drug X or treatment Y resulted in a 40% improvement of outcome for patient.

But what they don't say is people who didn't take the drug but avoided obesity and excess Alcohol, Drugs, Tobacco had a 70% better outcome.

Re: Intermittent fasting associated with increased risk of early death

#30
post #6

Earlier, on HN I read that it improves lifespan and now it is associated with early death.

Not the same thing... Also there can't be scientific evidence that anything improves lifespan.

Can you speak more to "Also there can't be scientific evidence that anything improves lifespan." I am missing the subtlety, but I would think statistically with twin studies and controlled experiments you could?
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