Use Native Client. You'll get as close to machine code as you'll ever get, while running in a sandbox. The only way to go faster is to fully trust the code on your machine.
Checkmate.
See, I can write the word checkmate, too. How many more times can we come up with a slightly better argument, using only one train of thought about what is actually a very complicated issue involving multiple vendors, multiple platforms, multiple standards committees, ease of use, ease of deployment, different memory, bandwidth, and cpu constraints, and then just say 'checkmate' as though everyone else is being completely ridiculous?
Several, I bet.