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Scientists discover receptor that blocks Covid-19 infection

sydney.edu.au

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Re: Scientists discover receptor that blocks Covid-19 infection

#71

Post by [deleted] »

PM_me_your_math wrote: post #44
binarymax wrote: post #20

To me the more interesting aspect of this research is the possibility to test susceptibility to severe infection. If you know ahead of time you are high risk, then the treatment and behavior is different than someone who knows they are low risk. Right now we treat everything the same - recommend everyone is vaccinated and everyone wear masks during outbreaks. I’d really like to know how at risk I am, and act accordin…

Comorbidities have always been indicators of risk. You're more likely high risk if you already have health issues, are morbidly obese, or over the age of 70.

[deleted]

Re: Scientists discover receptor that blocks Covid-19 infection

#72

Post by TEP_Kim_Il_Sung »

gadders wrote: post #60
AgentOrange1234 wrote: post #33

Earlier quoted context omitted.

(Disclaimer: covid averse, lost family member, upset with society for “being done.”) I’m not sure what to think about this. A year+ ago, I would have worried that folks would treat a low-risk evaluation as a permission slip to say “the pandemic is over for me,” stop masking/etc, and thus increase the aggregate spread of the virus to folks who are high risk. But now everyone is already doing that anyway. So yeah, it w…

[flagged]

Some masks do work.

https://www.3m.com/3M/en_US/respiratory-protection-us/produc...

Re: Scientists discover receptor that blocks Covid-19 infection

#73

Post by AnonymousPlanet »

gadders wrote: post #61
throwawaaarrgh wrote: post #38

Earlier quoted context omitted.

Sometimes I think I'm the only low risk person left on the planet wearing a mask and vaccinating. Then I see old folks or one 30y/o woman in the supermarket wearing a mask, and I remember that this protects them too. There's even some performers asking fans to mask up so high risk people can come to their shows. Gives me a tiny glimmer of hope for humanity.

[flagged]

"The high risk of bias in the trials, variation in outcome measurement, and relatively low adherence with the interventions during the studies hampers drawing firm conclusions."

Means they aren't sure themselves, if their results are usable at all. For the individual, one unmasked exposure undoes the entire effort. We're not talking about toxicity.

This seems to be clear to the authors aswell. The strongest language in their conclusions reads like this:

"There is uncertainty about the effects of face masks. The low to moderate certainty of evidence means our confidence in the effect estimate is limited, and that the true effect may be different from the observed estimate of the effect."

Going from that to "Masks don't work" is quite the leap.

Re: Scientists discover receptor that blocks Covid-19 infection

#75

Post by anonymouskimmer »

gadders wrote: post #62
PM_me_your_math wrote: post #44

Earlier quoted context omitted.

Comorbidities have always been indicators of risk. You're more likely high risk if you already have health issues, are morbidly obese, or over the age of 70.

[flagged]

So if it works for a person with a lot of bad habits you think it's a bad idea? Wouldn't something that works for a person with a lot of bad habits be even better?

Re: Scientists discover receptor that blocks Covid-19 infection

#76

Post by cableshaft »

qup wrote: post #63
SketchySeaBeast wrote: post #54

Earlier quoted context omitted.

I wear an N95 when I go out but only my regular glasses. I too haven't been sick since January 2020. I used to get colds pretty much quarterly, and so it's absolutely worth it to me. If it bothers someone else to see me wearing one that's their problem, I'm not asking them to wear one.

Has it bothered anyone?

I get the ocassional weird, sometimes mean look every once in a while, but I can deal with that as long as people don't stop and confront me over it, which thankfully hasn't happened yet, except a single time when some jerk walked past me and baa'd to suggest that I was a sheep back in 2020.

I don't even wear a mask everywhere (not since I got vaccinated). I don't once I sit at a table at a restaurant, or at certain social functions. But somehow I still haven't gotten Covid yet (that I'm aware of at least), even after a few known exposures, so I'm guessing either it's helping at least a little bit or I had an asymptomatic case a while back.

As far as I know, though, I could still have a moderate-to-bad case of it when I get it. My parents just both got it recently, for example, (that was one of my exposures, since they were helping me clean out my flooded basement just before they got symptoms) and it took both of them over a month before they got over it, and we share genes, so in theory I should have a somewhat rough time once I get it as well.

Re: Scientists discover receptor that blocks Covid-19 infection

#77

Post by don_neufeld »

anonymouskimmer wrote: post #52
PM_me_your_math wrote: post #47

Earlier quoted context omitted.

You're still touching things, then touching your face. You're still breathing the same air as everyone. You're still moving through clouds of expelled vapor from everyone who has walked in front of you recently. There is no hermetic seal around your nose and mouth if you wear a mask. Your eyes are exposed to the air. And if you wear the same mask more than once, you are trapping all sorts of bacteria and other nastie…

> You're still touching things, then touching your face. > Your eyes are exposed to the air. I'm not the person you're responding to. Just what I do. The mask covers the mucus membranes, except around the eyes. And I've got glasses with side-shields for the eyes. And an ASTM-III mask over the N95 mask so that I can touch and manipulate the masks without touching the breathing surface of the N95. > You're still breath…

I used to get them more than yearly, usually 3x or more per year, some of them were pretty brutal (Really bad coughs, fevers, night sweats, up to a week of PTO to recover)

I have masked every time I leave the house since COVID started impacting Wuhan (we had Chinese operations, so saw early impact on the business side. If you saw me masking on BART in early 2020, wave) and I haven’t gotten a single illness of any type since then.

It’s glorious.

I am often close to the only person I see all day masking, and it blows my mind why people don’t get this advantage.

Re: Scientists discover receptor that blocks Covid-19 infection

#78

Post by buggythebug »

superkuh wrote: post #8

That's good. But the lower lungs already get seepage of body serum/humoral igM and igG. If you really want to protect against infections then you have to induce mucosal immunity (and get tissue resident B and T cells) in the surface layer of the upper respiratory. Unfortunately intramuscular vaccinations do not do that, they only give serum/humoral immunity. So they're only the first step to protect against serious d…

What he said.

Re: Scientists discover receptor that blocks Covid-19 infection

#79

Post by delecti »

gadders wrote: post #62
PM_me_your_math wrote: post #44

Earlier quoted context omitted.

Comorbidities have always been indicators of risk. You're more likely high risk if you already have health issues, are morbidly obese, or over the age of 70.

[flagged]

Hypocrisy speaks less to the quality of someone's advice than it does to their willpower.

Re: Scientists discover receptor that blocks Covid-19 infection

#80

Post by anonymouskimmer »

don_neufeld wrote: post #77
anonymouskimmer wrote: post #52

Earlier quoted context omitted.

> You're still touching things, then touching your face. > Your eyes are exposed to the air. I'm not the person you're responding to. Just what I do. The mask covers the mucus membranes, except around the eyes. And I've got glasses with side-shields for the eyes. And an ASTM-III mask over the N95 mask so that I can touch and manipulate the masks without touching the breathing surface of the N95. > You're still breath…

I used to get them more than yearly, usually 3x or more per year, some of them were pretty brutal (Really bad coughs, fevers, night sweats, up to a week of PTO to recover) I have masked every time I leave the house since COVID started impacting Wuhan (we had Chinese operations, so saw early impact on the business side. If you saw me masking on BART in early 2020, wave ) and I haven’t gotten a single illness of any ty…

> if you saw me masking on BART in early 2020, wave

Which line, what time? :) I only started riding BART in late 2019, so only had a few months of it before stopping. I'm sure I would have been ill more often than yearly if my ridership had continued.

I agree. Additionally the masks will more than pay for themselves when it comes time to cash out my accumulated sick leave when I leave this job.

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