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Omega-3s: Are “Brain-Boosting” Effects Scientifically Backed?

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Re: Omega-3s: Are “Brain-Boosting” Effects Scientifically Backed?

#161

Earlier quoted context omitted.

What do you mean by P(TheScience) ?

The confidence we have that the relevant scientific prescriptions are true.

That’s an odd use of notation. Typically P(A|B) is used to denote probabilities of outcomes.

Re: Omega-3s: Are “Brain-Boosting” Effects Scientifically Backed?

#162

Earlier quoted context omitted.

You you can just buy cold pressed flax oil and supplement with that. ~30 USD for ~1L iirc and it has an absolute assload of ALA (omega3) Hemp seed oil is a good one for omega6 but usually people get enough 6 from diet and 3 is the one we need to boost to get the 3:6 ratio up https://en.m.wikipedia.org/wiki/Fatty_acid_ratio_in_food

ALA must be converted to EPA and DHA, which it does at less than 10% efficiency, so you'd need to consume an assload of it, too. Your best bet is still fish(oil).

Your efficiency statement brings the requirement to less than a tbsp a day (there's about 7 grams of ALA in a tbsp).

Re: Omega-3s: Are “Brain-Boosting” Effects Scientifically Backed?

#163

Earlier quoted context omitted.

The confidence we have that the relevant scientific prescriptions are true.

That’s an odd use of notation. Typically P(A|B) is used to denote probabilities of outcomes.

P(A|B) denotes the probability of A, given B: out of all the "possible worlds" where B is true, in what proportion is A true?

P(B) denotes the probability of B given no additional constraints: it's the same as saying P(B|true).

Re: Omega-3s: Are “Brain-Boosting” Effects Scientifically Backed?

#164

Earlier quoted context omitted.

The confidence we have that the relevant scientific prescriptions are true.

That’s an odd use of notation. Typically P(A|B) is used to denote probabilities of outcomes.

https://en.wikipedia.org/wiki/Bayesian_probability

Re: Omega-3s: Are “Brain-Boosting” Effects Scientifically Backed?

#165
post #55

Metaphor I learned from a biochemist: You are in a boat with holes in it (holes in this metaphor are nutritional deficiencies). To prevent the boat from sinking you patch the holes under waterline starting from the largest. The boat continues to sink until all holes under the waterline are patched. You don't stop sinking by patching one hole again and again. After you have patched all holes under the waterline you ca…

> ps. Body can synthesize omega-3 if there is enough α-linolenic acid (ALA) available. IIRC, ALA is an Omega 3 , just one the human body doesn't use for much. The body can synthesize EPA and DHA (which it does use), but humans are pretty bad at that. It's totally conceivable that the rate of synthesis evolved in the context of regular dietary intake of EPA/DHA, so never needed to provide for all the body's needs.

You are correct. Thank you.

Re: Omega-3s: Are “Brain-Boosting” Effects Scientifically Backed?

#166

Earlier quoted context omitted.

What do you mean by P(TheScience) ?

The confidence we have that the relevant scientific prescriptions are true.

Oh, prescriptions, that makes a lot more sense. As you rightly point out, science is not prescriptive, only descriptive.

Re: Omega-3s: Are “Brain-Boosting” Effects Scientifically Backed?

#167

Supplements are great because at worst they work like a placebo. There is a ton of evidence that placebos actually work better than real FDA approved stuff (in some cases) because there is a metric tonne of crap we don't understand about the brain itself and it's ability to heal the body. At best they actually affect the gut microbiome in some way (mostly probiotics) which, in many cases, are also backed by clinical…

I'd say that, at worst, they can be bad for you. You can overdose some of them. And if you're talking about herbal supplements, it's probably even worse than that, i.e. some of them can actively be bad for you (e.g. St. John's wort if you're taking other medications). And then, there's the problem of quality. Some supplements contain substances they shouldn't contain (e.g. heavy metals or others).

I'm a fan/user of supplements/nootropics, but they shouldn't be taken lightly.

Re: Omega-3s: Are “Brain-Boosting” Effects Scientifically Backed?

#168
post #43

Earlier quoted context omitted.

why is it that no one wants to study the effects of nootropics?

Because most of the time, interest in a topic is a function of plausibility. Most nootropics have little or nothing to indicate they work — not even a hint of something plausible. Of course, it’s possible the scientific community is overlooking something promising. This has happened before. But that’s a dangerous bet for a career scientist to take. Practically, if you want nootropics that work, and if you want to con…

Exercisium, diet-amate, and sufficient sleep-adine. Very powerful nootropics.
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