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Some gut bacteria appear to communicate with the brain

bbc.com

171–180 of 196 posts

Re: Some gut bacteria appear to communicate with the brain

#171

Earlier quoted context omitted.

I got the opposite experience. I have IBD and recently started on some potent probiotics. Suddenly my energy and focus went up 1000%. So this is how regular people healthy live wow. I used to be lethargic all the time for 30+ years.

Putting this out there in case it may help others: My mother suffered from GERD for years and years and about two years ago, her condition seemed to have taken a turn for the worse. We’re talking waking up in the middle of the night projectile vomiting. Constant heartburn, burping and indigestion after meals and daily constipation. The doctors were completely unable to help except to recommend antacids and possibly P…

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Re: Some gut bacteria appear to communicate with the brain

#172
post #156
post #132

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Just a comment, using the term "mainstream medical system" is a "code smell" for me when discussing medical science. Have you had your gut biota analyzed to see whether there is a basis for your inflammation issues? Yes, "big pharma" has a lot of control, but medical research is not entirely driven by them, particularly outside of the US. It sounds like you remade your gut biota via various paths. "Traditional" medic…

In german speaking countries gut microbiome analysis is considered alternative medicine by many medical professionals and is actively discouraged by some interest groups. [1] There always is a gap between medical research and application which people have different opinions on. For example when it was found out that high cholesterol was bad for you, doctors recommend patients with high cholesterol to eat less cholest…

According to the (4 year old) article there are no clinical studies showing that the gut microbiome analysis might be useful for either explaining or treating a chronic inflammation. That is pretty far from it being considered "alternative medicine"

Re: Some gut bacteria appear to communicate with the brain

#173

Our gut biomes and the gut-brain axis are pretty mind-blowing in the way they facilitate our behaviors and general mental/physical health. It's amazing how much we haven't figured out yet too...especially with neural pathways. Today's world of commercialized food (a few major foods/culprits in particular) throws inflammation at us in spades, and eating well has honestly made a huge difference in my life -- the most n…

what a wonderful resource. He has no reason for me to be skeptical but I have a hard time believing anything on youtube

Re: Some gut bacteria appear to communicate with the brain

#174
post #172
post #156

Earlier quoted context omitted.

In german speaking countries gut microbiome analysis is considered alternative medicine by many medical professionals and is actively discouraged by some interest groups. [1] There always is a gap between medical research and application which people have different opinions on. For example when it was found out that high cholesterol was bad for you, doctors recommend patients with high cholesterol to eat less cholest…

According to the (4 year old) article there are no clinical studies showing that the gut microbiome analysis might be useful for either explaining or treating a chronic inflammation. That is pretty far from it being considered "alternative medicine"

I had my gut microbiota sequenced twice. The results were not actionable at all, because there is very little knowledge about what constitutes a healthy microbiome. Those tests are great entertainment if you're curious about the subject. But that's about it.

We know that a diverse microbiome might be healthier than a non-diverse one. Exercise, eat your fibers, legumes, fruit and whole grains. Avoid processed food. Enjoy some fermented condiments. Avoid alcohol.

Re: Some gut bacteria appear to communicate with the brain

#175
post #172
post #156

Earlier quoted context omitted.

In german speaking countries gut microbiome analysis is considered alternative medicine by many medical professionals and is actively discouraged by some interest groups. [1] There always is a gap between medical research and application which people have different opinions on. For example when it was found out that high cholesterol was bad for you, doctors recommend patients with high cholesterol to eat less cholest…

According to the (4 year old) article there are no clinical studies showing that the gut microbiome analysis might be useful for either explaining or treating a chronic inflammation. That is pretty far from it being considered "alternative medicine"

They actively discourage its use: "Die Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) rät davon ab, Stuhltests zur Untersuchung des Mikrobioms zu nutzen."

In my opinion there being no evidence in either direction does not mean that you should not try it, especially if there is no downside and you have a chronic condition.

I assumed lack of evidence + non mainstream opinion = alternative medicine. Maybe there is a better word for cases like this where there is some evidence but no clear indication of causality.

Re: Some gut bacteria appear to communicate with the brain

#176

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I was told me esophageal sphincter doesn't fully close. Would apple cider vinegar help keep my acid low?

If you are overweight or have belly fat then it may be that your esophageal sphincter is fine and its your sleeping position that is causing the issue. Sleeping on your stomach causes belly fat to push into the area of your sphincter and opens it up slightly, now acids can flow past this point. The rise of esophageal cancer in the 90's up to now corresponds with the rise of obesity. I was actually allergic to NSAIDs…

These are good points and hopefully useful to other HNers.

I'm not overweight by more than a kilo or two, and I sleep on my back or side, so this doesn't match my case as much.

Re: Some gut bacteria appear to communicate with the brain

#177

For the folks that take probiotics: how did you decide what to take?

Trial and error. I've taken 6-8 different kinds and settled on one that works, which is the cheap generic store brand.

My wife has done the same, and has discovered that the one that works for her is a completely different sort.

Re: Some gut bacteria appear to communicate with the brain

#178

Earlier quoted context omitted.

Putting this out there in case it may help others: My mother suffered from GERD for years and years and about two years ago, her condition seemed to have taken a turn for the worse. We’re talking waking up in the middle of the night projectile vomiting. Constant heartburn, burping and indigestion after meals and daily constipation. The doctors were completely unable to help except to recommend antacids and possibly P…

Could you please point us to more information about this? My girlfriend suffers from similar symptoms (but less severe).

Note: I’m not a healthcare professional so please take anything I say with a grain and salt and be sure to do your own doctor consultations + research. This should not be taken as medical advice, its just what has been working in our case.

@myshpa posted a link above which I hadn’t seen before, that actually confirms many of my own independent observations: https://chriskresser.com/how-to-cure-gerd-without-medication...

What worked for her:

- 10-15 minutes before every meal, suck on a DGL (Deglycyrrhizinated Licorice) tablet. This will interact with saliva and cause the GI system to secrete mucus to protect itself from acid.

- During the meal, take a digestive enzyme that contains at least Betaine HCL, Bromelain and Papain which will help break down carbs and proteins and stop food from entering the gut half digested, which can cause gas production from fermentation.

- Take a probiotic supplement every night before bed (we’ve found 15 billion to be sufficient, but you can try ones that are less/more potent). If you need water to swallow, squirt a tiny bit of lemon juice into it first.

Diet-wise: Avoid things that will relax the LES such as caffeine, mint, chocolate, etc. Avoid anything with tomato skins and certain types of legumes (if you want to eat these, remove the skins). It can be difficult, but reduce sugar intake as much as possible. Try not to drink water while eating (it will dilute stomach acid) but if she needs to, its been my observation that a tiny squirt of lemon juice with water helps.

Eat fermented foods regularly like Kefir, Kimchi, Sauerkraut, yogurt, etc. These probiotics will need to consume fibre from prebiotics in order to not starve in the gut. Increase your intake of all kinds of high fibre whole foods. Kale, beans, broccoli, whole grains, potatoes, whole almonds, etc. Google “low FODMAP diet”.

Regular exercise is important. It can be something low intensity like walking. It helps stimulate the digestive system and gut activity. Do it before meals, preferably.

It can be counterintuitive, but I think the root cause of a lot of GERD symptoms is actually weak stomach acid. That article linked above summarizes it pretty nicely. If that’s the case, make sure your girlfriend is at least supplementing with vitamins C and D, plus a B-complex with Methylcobalamine. Low stomach acid can cause malabsorption of these nutrients and others.

Keep a log book. Every body is different, so every time there is an episode, be sure to record what was specifically eaten that day and then avoid that food.

Any other questions feel free to ask.

Re: Some gut bacteria appear to communicate with the brain

#179

For the folks that take probiotics: how did you decide what to take?

Pro-biotics in pill form are dubious at best. Even yogurts available in stores have been pasteurized for longer shelf life (not to speak of the loads of sugar added). Vegetables from the cruciferous family, like cabbage, broccoli, cauliflower, and home-fermented yogurt will give you the most bang for the buck. Fermented forms of cabbage like sauerkraut and kimchi are supposed to be especially good for your gut bacteria.

Re: Some gut bacteria appear to communicate with the brain

#180

Earlier quoted context omitted.

It will exacerbate esophageal irritation on the way down even if it did help a weak LES (which it doesn't). Please ask your doctor before trying this. Avoiding unadulterated high acid foods is a first line treatment for gastric problems.

Yup, no coffee / dark chocolate / dairy / alcohol / citrus for me for over a decade now, among other things. I don't miss any of it, except chocolate milk. I've seen vinegar recommended for GERD online before, but was curious whether there's much medical know-how behind it (studies or at least a clear theory of why it would help me vs. PPIs). With a weak LES (lower esophageal sphincter) a lot of "just do this" GERD f…

The "theory" behind ACV is that stomach problems can be caused by H. Pylori overgrowth due to acid underproduction. H. Pylori and stomach acidity problems are easily testable diagnoses via upper endoscopy on a case by case basis. What is NOT controversial however is the much higher vulnerability of the esophagus to acid (on the way up or the way down), pain from which damage is the "burn" in heartburn. The esophagus needs time to heal regardless of whether ACV would or would not help the stomach, and it'd definitely be harmful to the inflamed tissue up there. As I mentioned above, sodium alginate is a remarkably effective and safe treatment for mild and moderate GERD, which is picking up interest as PPIs are coming under intense scrutiny for possible harmful side effects long term. It's not a cure to anything per se, but this isn't medical advice either - people should root cause their stomach troubles with a qualified doctor.
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