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Making chloroform so I can sleep better at night [video]

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Re: Making chloroform so I can sleep better at night [video]

#91

Post by isk517 »

mrguyorama wrote: post #69
isk517 wrote: post #39

Earlier quoted context omitted.

Excuse me sir, but are you implying that in 1993 at WrestleMania 9 when Giant Gonzalez knocked out the Undertaker using a chloroform soaked rag that it was all fake? If so then mister, I think you are full of crap. /s

Professional wrestling got a lot more fun and cool when I realized it isn't "fake", because it isn't trying to be real because it's actually supposed to be modern day Shakespeare

I loved watching it as a kid and my friend convinced me to check out some modern stuff about 2 years ago and I have been having a blast watching it ever since.

Re: Making chloroform so I can sleep better at night [video]

#92

Post by ok_computer »

gus_massa wrote: post #2

The author is Chemdelic. I was expecting a video by Nile Red, but I was not disappointed. (As the video explain, don't try this at home unless you have a degree in Chemistry or something. That invisible fumes looks nasty.)

Even doing this with a chemistry background is incredibly irresponsible. There’s more than personal know how at work in industrial and academic labs. Fume hood stacks well above grade and incinerators and permits or registration. Plus the waste disposal issue and byproducts. This brand of youtube entertainment is super bad. Same thing with people extracting mercury or whatever. Like what is the best end case: you’ve done bench work in your neighborhood and are a point emitter of byproducts and create a product that have no real end use. Chlorinated solvents are no joke and making a carcinogen for youtube views is beyond dumb. I’d call the cops if I saw my neighbor doing some home cooking like this it’s not well thought out and just selfish and irresponsible.

Re: Making chloroform so I can sleep better at night [video]

#93

Post by azalemeth »

kortex wrote: post #79
xkcd-sucks wrote: post #18

Chloroform is great for extractions (if you don't care about the environment) because it sinks to the bottom of a sep funnel, but the thing about it being a knockout gas or sleep aid is complete BS. Based on an unpublished study of about 4 degenerate chemistry undergrads: - It PROBABLY takes several minutes of inhalation through a saturated rag to induce full loss of consciousness, although shorter times do produce n…

> The poor efficacy of DMSO in assisting drug translocation through skin Oh yeah, for the observer gallery: The reason DMSO (and DMF, DMAc, HF, to an extent haloforms, and polar aprotic solvents in general) are dangerous is that they can dissolve and transport small molecules (under 1000 daltons, possibly more) through your skin and into the bloodstream. They go straight through nitrile, vinyl, and latex gloves. You…

The garlic like smell of DMSO just doesn't leave you if it gets into your skin. It's "safe" but really, really bad to have fingertips smelling of it for days. I wish I had those bovine gloves during my PhD...

Re: Making chloroform so I can sleep better at night [video]

#94

Post by jefftk »

toss1 wrote: post #82
joosters wrote: post #51

Earlier quoted context omitted.

But my lab manager did walk in at one point and immediately recoiled from the fumes (which we were nose-deaf to at that point). I don't know whether it's true or not, but I remember a chemistry lecturer telling me that you don't need to worry about terrible smells in the lab, our noses are sensitive to extremely miniscule levels of chemicals. It's when the levels are so high that they have overpowered our senses and…

Yup, similar to frostbite. Normal skin temp is around 86°F. as it is cooled, it goes from cool to cold sensation, to very painful at around 55°F. Below that, you don't feel anything as it continues to cool to the point where it freezes solid (which wouldn't be a problem if the freeze-thaw cycle didn't create so many little spiny ice structures that break the cell walls; a type of frog has 'anti-freeze' in it's makeup…

> a type of frog has 'anti-freeze' in it's makeup so it can freeze and re-thaw

Nit: it can't actually recover from freezing solid. It just has lowered the freezing point of the remaining liquid to below the temperatures it's going to encounter.

Re: Making chloroform so I can sleep better at night [video]

#95

Post by dalyons »

pcthrowaway wrote: post #62
dalyons wrote: post #14

Earlier quoted context omitted.

Pro tip: make it boiling hot. I knocked myself out instantly (but briefly) by accidentally breathing in over a boiling chloroform vat at a biotech internship. Came to a few seconds later on the floor. (Don’t actually recommend)

Did anyone see it happen? Were you close to falling in?

Fortunately it was in a busy lab so I was noticed! The boiling retort/bath was only a bit larger than head size, so technically possible to fall in but thankfully not :)

Re: Making chloroform so I can sleep better at night [video]

#96

Post by dalyons »

xen2xen1 wrote: post #70
dalyons wrote: post #14

Earlier quoted context omitted.

Pro tip: make it boiling hot. I knocked myself out instantly (but briefly) by accidentally breathing in over a boiling chloroform vat at a biotech internship. Came to a few seconds later on the floor. (Don’t actually recommend)

Was that the chloroform or hypoxia like someone mentioned? Seems the second would be much more dangerous?

Maybe! I’m no expert. But it was a really quick situation - lid popped, I looked in , there was boiling chloroform when there was supposed to be a different reagent (due to a software bug in the machine). Down I went. So probably not time for hypoxia? Fun bug report to write haha

Re: Making chloroform so I can sleep better at night [video]

#97

Post by labrador »

schwartzworld wrote: post #90
labrador wrote: post #48

Earlier quoted context omitted.

Let's see there's 50 whippets in a box, 12 boxes in a case. I did a couple hundred cases before I finally stopped. My last two binges 5 years apart were 15 cases over a 2 week period and 20 cases over a 10 day period. Once I start cracking whippets I can't stop. It felt almost like an OCD thing.

It's called hippie crack for a reason.

I didn't know that when I started. I was thinking of "the nitrous philosopher" William James. Later I heard hippie crack. Yep.

Re: Making chloroform so I can sleep better at night [video]

#98

Post by nwiswell »

azalemeth wrote: post #93
kortex wrote: post #79

Earlier quoted context omitted.

> The poor efficacy of DMSO in assisting drug translocation through skin Oh yeah, for the observer gallery: The reason DMSO (and DMF, DMAc, HF, to an extent haloforms, and polar aprotic solvents in general) are dangerous is that they can dissolve and transport small molecules (under 1000 daltons, possibly more) through your skin and into the bloodstream. They go straight through nitrile, vinyl, and latex gloves. You…

The garlic like smell of DMSO just doesn't leave you if it gets into your skin. It's "safe" but really, really bad to have fingertips smelling of it for days. I wish I had those bovine gloves during my PhD...

> fingertips smelling of it for days

It's even more insidious than that -- it is not only your fingertips that smell, since it penetrates the skin so readily. Pure DMSO itself is odorless, but it is metabolized into DMS, which stinks unbelievably strongly of garlic. The DMS has a very high systematic half-life (38 hours!!!) and remains dissolved in the blood, meaning your blood itself will stink of garlic for days after exposure.

The gut punch, however, is that the victim is reportedly unable to smell it (probably because their olfactory tissue is literally awash in DMS), so they don't realize they smell like walking garlic bread.

Re: Making chloroform so I can sleep better at night [video]

#99

Post by FPGAhacker »

kortex wrote: post #23
xkcd-sucks wrote: post #18

Chloroform is great for extractions (if you don't care about the environment) because it sinks to the bottom of a sep funnel, but the thing about it being a knockout gas or sleep aid is complete BS. Based on an unpublished study of about 4 degenerate chemistry undergrads: - It PROBABLY takes several minutes of inhalation through a saturated rag to induce full loss of consciousness, although shorter times do produce n…

> Join us for our continued lecture series, covering topics such as Please share/blog these! I too have several degenerate chemistry undergrad stories. > The poor efficacy of DMSO in assisting drug translocation through skin Yep. During one particularly sleep-deprived finals week, and after recently learning about DMSO's transdermal transportation abilities, my friend and I tried making caffeine skin patches. It work…

[flagged]

Re: Making chloroform so I can sleep better at night [video]

#100

Post by throwawaymaths »

kortex wrote: post #73
zoklet-enjoyer wrote: post #43

Earlier quoted context omitted.

You have to really dilute DMSO if you're going to put it on your skin.

I mean, pure DMSO on the skin feels fine, albeit not the safest.

Can you not taste the garlic in your mouth for hours after?
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