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Some gut bacteria appear to communicate with the brain

bbc.com

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Re: Some gut bacteria appear to communicate with the brain

#71

Post by user1029384756 »

unsupp0rted wrote: post #43
user1029384756 wrote: post #37

Earlier quoted context omitted.

Putting this out there in case it may help others: My mother suffered from GERD for years and years and about two years ago, her condition seemed to have taken a turn for the worse. We’re talking waking up in the middle of the night projectile vomiting. Constant heartburn, burping and indigestion after meals and daily constipation. The doctors were completely unable to help except to recommend antacids and possibly P…

What are the side-effects for PPIs? I've been taking them for almost 2 decades for GERD without anything too specific coming up. I check my B12 levels from time to time and they seem ok. My hemoglobin is always a bit low and iron supplements don't seem to help. What other things are common with long-term PPI use?

I am not in any way shape or form a medical professional, but there do seem to be some studies that show there is evidence of an increased risk of gastric cancer with long term PPI use. Again, not a medical professional, so if it works for you and suits your personal risk tolerance, please don’t let a random internet commenter freak you out.

Re: Some gut bacteria appear to communicate with the brain

#72

Post by lofaszvanitt »

yosito wrote: post #7

In the last three years, something related to my gut-brain connection got fucked. I'm not sure if it was some kind of post-viral inflammation causing stress, or stress of isolation causing inflammation. But it's definitely a two way street and mine got completely stuck in a feedback loop. The mainstream medical system failed to help me. Eventually some functional medicine doctors managed to help me improve via diet,…

do abs exercises every even day that work your lower, middle and upper abdomen. do these until you can't anymore, each part. It increases blood flow to your gut and speeds up the recovery process.

Re: Some gut bacteria appear to communicate with the brain

#73

Post by fragmede »

sva_ wrote: post #52
thinkingemote wrote: post #33

I get gut pain sometimes, on a semi regular basis. The day before the pain hits I have mild-euphoria, clear thinking, positive outlook, lots of energy, more social and extravert. It's not normal. Something is going on with the brain and my gut. It's possible that it's endorphins being released to stop any pain ... but this is about 24 hours before the crippling cramps start, and it's more a mood shift than pain killi…

> The day before the pain hits I have mild-euphoria, clear thinking, positive outlook, lots of energy, more social and extravert. It's not normal. Some might say that you got it backwards and this would be preferably your "normal". First thing I'd do would probably be to document in detail what you're eating on those days and if any pattern emerges. Try eliminating things, if there is any pattern. Sounds a lot like l…

how'd you get rid of it?

Re: Some gut bacteria appear to communicate with the brain

#74

Post by arminiusreturns »

NoPicklez wrote: post #59
yosito wrote: post #7

In the last three years, something related to my gut-brain connection got fucked. I'm not sure if it was some kind of post-viral inflammation causing stress, or stress of isolation causing inflammation. But it's definitely a two way street and mine got completely stuck in a feedback loop. The mainstream medical system failed to help me. Eventually some functional medicine doctors managed to help me improve via diet,…

The challenge I think modern medicine has is that in order to prescribe a solution it does need to understand the problem and how your gut might be responsible for it. As we know the medical world takes time to adapt and so it takes more than just a few studies to require doctors and GP's to understand it, better yet be equipped to prescribe a solution. For many of these gut health related issues, I think most people…

I was part of genetics boom when sequencing dropped in price, and I thought that situations just like this were what the market was poised to capitalize on, sequencers in every doctors office or at least cheap enough and prolific enough that sequencing a micriobiome would give doctors data to work with.

The sad reality is that many doctors are operating with what data scientists would reject as missing or bad data, the solution (ignoring the money side) is to get them into a pattern of collecting more data and being better at analysing it.

Each microbiome is different, and I think until sequenced and analyzed, it is simply guessing on the part of patient and doctor.

Re: Some gut bacteria appear to communicate with the brain

#76

Post by manav »

d23 wrote: post #30
popotamonga wrote: post #23

Earlier quoted context omitted.

That one exactly. Expensive as crap and hard to find in my country but it's priceless.

What's up with this? https://vsl3.com/assets/v1/patient/files/FactSheetVSL3Jun202... Just went to their site and it sketched me out a bit to read this.

It is a patent dispute, from what I can recall visbiome is the one with the legitimate claim and original inventor.

Re: Some gut bacteria appear to communicate with the brain

#78

Post by keyP »

MacsHeadroom wrote: post #60
keyP wrote: post #48

Ayurveda posited a form of gut-brain axis thousands of years ago (and is a core basis for its dietary aspects), interesting to see more scientific research delving into the details.

Ayurveda posits that palm reading is legitimate medicine. The notion that gut health impacts mental wellbeing is obvious. The specifics of it are less so.

Not sure what your point is here. I'm suggesting that dietary aspects were designed around the aspect of a gut-brain axis and praising that more research is going into the details. Similar to how we're seeing more research in the field of meditation and its impact on brain structure.

Source on Ayurveda posits that palm reading is legitimate medicine?

Re: Some gut bacteria appear to communicate with the brain

#79

Post by myshpa »

unsupp0rted wrote: post #43
user1029384756 wrote: post #37

Earlier quoted context omitted.

Putting this out there in case it may help others: My mother suffered from GERD for years and years and about two years ago, her condition seemed to have taken a turn for the worse. We’re talking waking up in the middle of the night projectile vomiting. Constant heartburn, burping and indigestion after meals and daily constipation. The doctors were completely unable to help except to recommend antacids and possibly P…

What are the side-effects for PPIs? I've been taking them for almost 2 decades for GERD without anything too specific coming up. I check my B12 levels from time to time and they seem ok. My hemoglobin is always a bit low and iron supplements don't seem to help. What other things are common with long-term PPI use?

Have you tried apple cider vinegar (ACV)? Works wonders.

PPIs don't really treat GERD, imho it's one of those medicines to be used perpetually (good only for shareholders).

https://www.youtube.com/watch?v=qTzxfoL82n8 - good explanation why/how ACV works and why PPIs don't, iirc

Re: Some gut bacteria appear to communicate with the brain

#80

Post by ThinkBeat »

News or articles about this keep coming out recently. but they all seem to be limited to "we think", "might" and the great potential it may have.

Since we do not know much about how the brain works to begin with I guess that is as close as we can get.

I say we dont know much about how the brain works as a I take medication for depression.

The way that works most often is that you are given a pill that may work. You take it for between 2 - 26 weeks, depending on results. (some may have a fast negative effect) and then you tell your doc if you feel better. (Sometimes complicated surveys)

if it didn't work, you get to do it over again. and again and again. until you find something that works, give up or die.

then sometimes it stops working.

One place I know does a cool, I forget the proper name. They take a "video" of how your brain is "working" (at an extremely low resolution). then they compare what they find to knowledge about what parts of the brain should be active, not active etc. From this they hope to establish a delta between "normal" and you.

Then you get to take pills and you come back (after some times) they do the whole thing over again, to see if you are now closer to "normal" or not.

The goal then being to find a chemical that brings you as close to normal as can be.

It is highly appealing in that it would offer -some- scientific basis for evaluating the drugs aside from "How do you feel".

If it -actually works- I have no idea. It was far too expensive for me, and to qualify you have to not have taken any medication already. (that would mess up the "virgin" recording).

An interesting research project would be recording tens of thousands of people who self-reported no depression in the hope that some would develop clinical depression and comparisons could be made.

If we now mix in gut bacteria into the equation, I can imagine you somehow "insert" new gut bacteria into a person and then you wait for some time and tell the doc if it worked or not. If not you can get a different psychobiotics and enter the loop. Add in regular medication for depression the number of possible permutation would become huge.

(I like to include this link to a Standford lecture on the difference between "being sad" and clinical depression https://www.youtube.com/watch?v=NOAgplgTxfc)

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