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Ask HN: What is the weirdest or most surreal recent technology you have seen?

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Re: Ask HN: What is the weirdest or most surreal recent technology you have seen?

#231

If you're not in the bio field, you may not be aware just how routine genetic modification has become. For the larger companies, projects can involve thousands of different iterations on DNA sequences, all of which are created, put in a cell, grown, sequenced, and analyzed. It's absolutely routine at this point - it's not a science or even engineering challenge project it's an operations project. The one that really…

If I were to restart my career, this is likely the field I'd pursue. I read The Gene: An Intimate History by Siddhartha Mukherjee last year and just became enraptured in the possibilities. I'm wondering if there's anything I can contribute to that field as someone with general programming capabilities.

> I'm wondering if there's anything I can contribute to that field as someone with general programming capabilities.

Oh there Absolutely is!

In general, there are four really high impact areas for computer folks - automation of lab equipment allows for scaling the number of experiments and the data that can be gathered by orders of magnitude; data science and engineering to sort, catalog, and investigate that data; building and scaling scientific computing systems to run analysis repeatably at scale; and even standard application building to manage and improve the overall process of tracking experiments and coordinating between groups.

The scientists and bioinformatics folks are very good at what they do, but someone who really understands how to build, manage, and scale software systems is an enormous force multiplier. If you're interested in the field, I really strongly recommend it.

Re: Ask HN: What is the weirdest or most surreal recent technology you have seen?

#233
post #11

Maybe not weird or surreal enough for HN. But I am amazed by the stability and quality of videos from my drone. It's just amazing that I could easily fly a kilometer away whilst having a live feed of the footage being streamed back to my controller. I have a sub 250g drone, so it's so light yet easily able to withstand pretty strong winds and the videos look great on a big 4K TV afterwards!

It seems like every amateur or even personal production has these big beautiful sweeping aerial shots now, when 10 years ago it would be only available to medium size productions that could rent a commercial drone, and 20 years ago only available to large productions that could afford to rent a helicopter.

The original "Planet Earth" was a showpiece for HD, but also these kinds of sweeping shots that people had rarely seen before. These were done with heavy cameras and complicated wire systems run through caves and forests. Today it seems almost pedestrian and quaint.

Re: Ask HN: What is the weirdest or most surreal recent technology you have seen?

#234

Earlier quoted context omitted.

If I were to restart my career, this is likely the field I'd pursue. I read The Gene: An Intimate History by Siddhartha Mukherjee last year and just became enraptured in the possibilities. I'm wondering if there's anything I can contribute to that field as someone with general programming capabilities.

Except somehow the required education is much higher and the pay is much worse than software, right? I’m personally surprised we don’t have 20x as many people working in biotech.

There's sort of a running joke with how the market treats biotech as well - a bio company could announce they'd cured death and get a 5% bump in their stock price, whereas a tech company says the word "blockchain" and doubles their share price. As a software engineer, you can get pay into the ballpark of what you'd get elsewhere, but you should probably just ignore the "equity" section of that offer letter.

Re: Ask HN: What is the weirdest or most surreal recent technology you have seen?

#235

Some of the VR movies are getting quite good. First the newer generation headsets- 2K, 90+ fps, cableless- no longer induce nausea. Second, movie makers are becoming versant with the strengths and limits of this media. One I saw in December called Container, I felt I was in the room with various scenes of realistic 3D people.

Agree, even the 2D version of the “Container” trailer looks interesting:

https://m.youtube.com/watch?v=gUysXcyNXAo

Re: Ask HN: What is the weirdest or most surreal recent technology you have seen?

#236

Earlier quoted context omitted.

I agree that the output is often wrong despite looking right, but in this instance I don't see anything wrong in this example.

Dijkstra's cannot be used as generally as described. A-star can potentially be more general, but that's highly dependent on heuristic. Dinkstras is a-star with a "min weight on shortest path first" heuristic. Because a star doesn't expand shortest paths first necessarily, it cannot necessarily find the shortest path to any node except the prescribed endpoint. Dijkstra's will find all shortest paths with cost less tha…

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Re: Ask HN: What is the weirdest or most surreal recent technology you have seen?

#237

Earlier quoted context omitted.

If I were to restart my career, this is likely the field I'd pursue. I read The Gene: An Intimate History by Siddhartha Mukherjee last year and just became enraptured in the possibilities. I'm wondering if there's anything I can contribute to that field as someone with general programming capabilities.

Except somehow the required education is much higher and the pay is much worse than software, right? I’m personally surprised we don’t have 20x as many people working in biotech.

i imagine a big reason for this is that we don't have a silicon valley of biotech pumped with VC money. and presumably a big reason for that is there's all kinds of red tape when it comes to health and humans. no such thing as "disrupting" if you're going to violate some intense laws and then get arrested for it or get your labs shut down. or even worse, the potential resulting violence from fundamentalists surrounding your campus, or stalking employees. scary stuff

Re: Ask HN: What is the weirdest or most surreal recent technology you have seen?

#238

USB-C/Thunderbolt is amazing. It blows my mind that you can have a graphics card, plus peripherals, plus storage, all connected by a single cable through a single, hot-pluggable(!) port.

> through a single, hot-pluggable(!) port

Don't forget reversible too!

Re: Ask HN: What is the weirdest or most surreal recent technology you have seen?

#239

Earlier quoted context omitted.

In fairness, Keanu Reeves, like Kristen Stewart, isn't the hardest person to deepfake…

Is this because both are actors and therefore there is lots of available training data? Or something even more specific to these two people?

Keanu Is weaved into the source code of this simulated world.

Re: Ask HN: What is the weirdest or most surreal recent technology you have seen?

#240
post #237

Earlier quoted context omitted.

Except somehow the required education is much higher and the pay is much worse than software, right? I’m personally surprised we don’t have 20x as many people working in biotech.

i imagine a big reason for this is that we don't have a silicon valley of biotech pumped with VC money. and presumably a big reason for that is there's all kinds of red tape when it comes to health and humans. no such thing as "disrupting" if you're going to violate some intense laws and then get arrested for it or get your labs shut down. or even worse, the potential resulting violence from fundamentalists surroundi…

TBF, San Diego and Boston are the centers for Biotech. The issues you raise are the correct ones.
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