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Long Covid: major findings, mechanisms and recommendations

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151–160 of 229 posts

Re: Long Covid: major findings, mechanisms and recommendations

#151
post #82

Earlier quoted context omitted.

> This is such a strange virus. This effect was previously known as post-viral fatigue. It's not unique to covid.

What is unusual is how long it lasts and, to some extent, how severe it can be.

Not really it's just got various names. chronic fatigue syndrome, postural orthostatic tachycardia syndrome, post viral fatigue...

Even straight up depression. When billions of people catch the same virus unintuitive things happen.

Maybe it's a strange virus (by what metric?) But it was definitely psychologically a very strange time.

Re: Long Covid: major findings, mechanisms and recommendations

#152
post #5

As always, it is difficult to assess this sort of thing without a reference to the flu. As far as I can tell, in daily life we are continuously encountering people with various chronic problems and systemically under-calling the impact of them. It is a total coincidence if a body is functioning at full capacity. If COVID increases the hazard ratios there isn't much I can do. As far as I can tell, everyone is going to…

>As far as I can tell, everyone is going to get COVID Not if everyone gets antibodies first.

I had the initial two Pfizer shots, then a Moderna booster. Had a strong immune reaction to the second and third shot. Still got Covid 7 months later. Unless people are very careful, I suspect everyone is going to get it.

Re: Long Covid: major findings, mechanisms and recommendations

#153
post #82

Earlier quoted context omitted.

I feel for you. This is such a strange virus. My whole family got covid so I expected to be next. But I only needed to take 2 days off at work and I paused my training for just 3 days and was almost back to my normal HR/pace in less than a week since I got first symptoms. It took me 3 more weeks before I started getting negative test results.

> This is such a strange virus. This effect was previously known as post-viral fatigue. It's not unique to covid.

[deleted]

Re: Long Covid: major findings, mechanisms and recommendations

#154
post #45

This is really bad. Important points: * About 10% of people getting COVID get some form of long COVID. * There's long term damage. At least years. Maybe permanent in some cases. * You can get COVID more than once.[1] Somewhere above 6-10% of infections are re-infections, and that number increases over time. Immunity seems to last 3-18 months. What is this going to look like in 5 years? 30% - 40% of the population dis…

I’ve had COVID multiple times — I collect variants like Pokémon cards. The first one (pre-vaccine!) was nasty with a few lingering effects that went away after a month, the last was asymptomatic. In everyone I know that has had multiple infections — which is a lot of people these days — subsequent infections are much less consequential than the last, including lingering effects. This is what you would generally expec…

I have a really crappy immune system - colds usually last three weeks for me. That said, my delta infection was probably 95% as bad as my infection with the original strain. Both times I had a fever of over 102f for about two weeks.

Again, though, I’m unique. Go me.

Re: Long Covid: major findings, mechanisms and recommendations

#155

I’ve been dealing with long COVID since March last year. There’s some interesting learnings I’ve had along the way: - I was almost perfectly healthy and in my early 30’s. Long COVID isn’t that rare and can happen to anyone, even with a mild case of COVID. - After first getting COVID, I didn’t rest much. There’s research showing this increases chances of getting long COVID. If you test positive… rest and fully recover…

[dead]

Re: Long Covid: major findings, mechanisms and recommendations

#156
post #92

Earlier quoted context omitted.

Maybe I'm being generous to the parent, but I also would like a comparison to the flu. Not because I don't believe covid is significantly worse (when I got it, it was way worse than the flu), but because I don't have a medical background and it is difficult to contextualize the actual risks here without some baseline where I have a decent intuition already built around. But where I disagree with the parent is the nee…

But have you actually had the flu? I ask, because most people say “oh, I had the flu” when in actuality they just had a common cold. The flu, the real flu, knocks you on the ass so hard that you actively start considering that death is a possibility and that heading over to the hospital would be a good idea. I’ve had the flu perhaps twice. Once as a child, once in my early 50s. The latter completely recalibrated my u…

It is bad. I had a few of them during my life. When I was eleven the flu triggered a reaction in my body, destroying the insulin producing cells from my pancreas. I've had a type 1 diabetes since then.

Nowadays in Finland (where I am from), they recommend flu vaccinations for kids who have type 1 diabetes in the family to reduce the risk of catching it.

Not all flus are bad to all of us, but if you catch the right strain, it can really knock you out.

Re: Long Covid: major findings, mechanisms and recommendations

#157
This is very comprehensive and highlights the major challenges with something so novel. I hope more doctors read up on these challenges. I’ve been lucky to have doctors advocate for me recently now that more research is coming out.

Especially around diagnosis, markers, and treatments. Many are just self diagnosing given many cannot find any underlying cause.

While I’m one of the unlucky ones who gets long Covid with each infection, many are throwing darts at what helps manage their day to day symptoms. The good news in my case is each long covid bout is shorter than the previous.

Here’s my story: https://jondouglas.dev/long-covid/

Re: Long Covid: major findings, mechanisms and recommendations

#158
post #42

Earlier quoted context omitted.

> Additionally new research is uncovering serious and significant risks for the vaccine with fairly marginal protection benefits. Could you provide a link to that research ?

[flagged]

Have not ghosted and many links provide by me and others. My observation is that for people who have had covid, like me, I’ve had it twice actually, once early on, so Alpha, and then post vaccination, more recently, so an Omicron variant. For these people like me who experience symptoms described as long covid, the following 3 observations are absolutely true and justified by lots of scientific published research:

(1) mRNA vaccinations can actually worsen long covid symptoms for a significant percentage of people. This is a fact.

(2) each day we are learning additional risks of vaccination. we even have a study using mice that can explicitly link the exact mechanism of cardiovascular damage caused by mrna vaccine. Also it’s very odd that suddenly anything that mentions VAERS is automatically junk science, especially as the system was created for exactly this problem. Objective analysis that accounts for reporting biases is showing serious and very statistically significant risks. Even CDC is increasingly acknowledging this as we learned this week.

(3) the marginal benefits of boosters is extremely small for most of the population, except perhaps some high risk segment. and even worse we now have studies indicating repeat mrna vaccination can have a negative impact on immune system.

Why these 3 points are so controversial when they are clearly true is simply evidence that the topic is completely politicized now. Unfortunately.

Re: Long Covid: major findings, mechanisms and recommendations

#159

COVID-19 is no joke. I know people want to move on with their lives, but people should stick to N95/KN-95/KF-94/FFP2/FFP3 masks for the time being unless we want to create a massive health care crisis and ruin the global economy as the if people get reinfected every few months, this would be imminent!

Strongly agree. It’s been frustrating to deal with this at work. I’m at a FAANG, and we’re required to come in 3 days a week. Coworkers came in visibly sick coughing away without wearing a mask. I wrote to people support and they say they can’t do anything about it, just recommend that I wear a mask and that’s about it.

Re: Long Covid: major findings, mechanisms and recommendations

#160
post #92

Earlier quoted context omitted.

Maybe I'm being generous to the parent, but I also would like a comparison to the flu. Not because I don't believe covid is significantly worse (when I got it, it was way worse than the flu), but because I don't have a medical background and it is difficult to contextualize the actual risks here without some baseline where I have a decent intuition already built around. But where I disagree with the parent is the nee…

But have you actually had the flu? I ask, because most people say “oh, I had the flu” when in actuality they just had a common cold. The flu, the real flu, knocks you on the ass so hard that you actively start considering that death is a possibility and that heading over to the hospital would be a good idea. I’ve had the flu perhaps twice. Once as a child, once in my early 50s. The latter completely recalibrated my u…

Yeah, my experience with swine flu was at least as bad as COVID...
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