Earlier quoted context omitted.
Over the course of the past 2 decades we've gone from "perhaps some day we'll find extra solar planets" to "most if not all stars have planets". JWST's already found water. At this point it's no longer a matter of if but when extrasolar life will be confirmed, and with which instrument. Might be JWST, might be WFIRST, might be HabEx.
By the standards of astrobiology, none of those instruments are capable of detecting life. But they might detect telltale signatures of biosphere in extrasolar atmospheres, which will trigger decades of debate as to whether there is life.
My understanding was that life would be "detected" by finding chemical signatures in the atmosphere which could not exist at a "steady state" without biological creatures there doing things. Is this what you mean by telltale signatures?
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