Chirality is an interesting topic, and controlled chiral synthesis is pretty cutting-edge chemistry. The real masters of this art are biological enzymes, i.e. the proteins that catalyze all chemical reactions. A lot of the modern catalysts used in chiral synthesis are themselves chiral, which is essentially mimicing the biochemical approach.
For this to work, however, the starting molecule needs to be what called pro-chiral. For illustration, imagine a flat triangular sheet of paper with three different elements at the points. How could you only label one side of that sheet? Well, if you take a copy of that triangle and glue one side to a table, then there's only one orientation in which all three points of the other triangle will make a one-to-one correspondence. This corresponds to the enzyme (glued to the table) specifically binding the pro-chiral molecule (i.e. a carbon atom with three different substituents) and then the free surface of the triangle is where the reaction takes place.
I suppose someone could develop such a system for amphetamine synthesis and it would qualify as 'green chemistry' (which really just means producing the desired product without generating a waste stream via a closed-loop process), and this might even be how it's done in the legal pharmaceutical world today (methamphetamine is sold as Desoxyn for ADHD treatment). There are better things for chemists to put their time and energy towards, in my opinion.
As far as the legality and safety of drugs, it seems pretty clear that criminalization just fills prisons while generating large profits for organized crime cartels, with many associated problems (i.e. violent crime), while not reducing the population of drug addicts. A public health approach based on educating people about the very negative health and social effects of drug and alcohol addiction seems like the more reasonable approach. Bans on advertising and promotion of drugs might be wise as well, as has happened with tobacco and alcohol to some extent.