‘Breakthrough’ obesity drugs that have stunned researchers

Post by jallen_dot_dev » Thu, Jan 05, 2023, 9:05 AM UTC

etothepii wrote: post #699

heavyset_go wrote: post #669

Earlier quoted context omitted.

> It’s so hard to eat healthy, I honestly cannot fathom how people do it. Learn to cook well so that eating out would result in lower quality meals compared to what you could make yourself. Once you're controlling what goes into your meals, instead of outsourcing it, that makes it easier to control portion sizes, how much fat/oils go into things (I've found that restaurant dishes have an absurd amount of fat in them…

There's a lot of words here so you took some time to write this. Who is it for? Why do you think this is a new/novel idea the person you are replying to, and others reading it, has/have not heard before?

Post by andromeduck » Thu, Jan 05, 2023, 9:16 AM UTC

markus_zhang wrote: post #761

bioemerl wrote: post #182

> In the past, scientists and the public often thought that those with obesity simply lacked the willpower to lose weight. But evidence is growing that most people’s bodies have a natural size that can be hard to change. In the context where we have gone from obesity rates of 13 percent to 40, to suggest that people have a natural weight and that's the cause of this seems absurd to me.

For me it's 80KG. Once it goes over 80KG I would gradually feel all kinds of bad things so I'll start to lose weight, but then it's so easy to get back. I don't really think willpower helps here. I mean unless I can do it for the whole life, it will bounce back quickly.

Post by urthor » Thu, Jan 05, 2023, 9:23 AM UTC

darkwater wrote: post #365

dcolkitt wrote: post #304

Earlier quoted context omitted.

You haven't controlled for body weight changes though. Nobody doubts that diets (if adhered to) can reduce weight. So if biomarkers improve relative to an alternative diet, the question is it because A) the Med diet is more effective at weight loss, or B) the Med diet has benefits outside weight loss. The research you linked is interesting, but confounded by weight loss. Research that has directly tried to control fo…

You just forget that there might be side-effects showing up in the long-run that we simply don't know yet (and possibly), why the mediterrean diet has been tested for a few hundred years already (where "diet" means what we have access to and eat, and not a small subset of foods forced on us that relies on a lot of mental effort to follow)

Post by urthor » Thu, Jan 05, 2023, 9:27 AM UTC

narrator wrote: post #709

The big elephant in the room is where did everyone's endogenous GLP-1 peptide go? A similar elephant in the room is why is synthetic thyroid hormone to replace all the missing endogenous thyroid hormones such a high selling drug? What in the environment is slowly poisoning everyone so their bodies don't work normally? Here's a clue, one of hundreds in the medical literature: "The endocrine disrupting potential of mon…

Post by phpisthebest » Thu, Jan 05, 2023, 9:36 AM UTC

kergonath wrote: post #825

fortran77 wrote: post #718

Earlier quoted context omitted.

[flagged]

> But it's always true that if you manage to eat fewer calories than your body needs each day you will lose weight. No, not necessarily. Several studies have shown that different people can get different amounts of energy out of the same food, depending amongst others on their gut micro biome, though stress also seems to play a role. It’s never going to be that simple. > the laws of thermodynamics won't fail Conventi…