What causes Alzheimer's? Scientists are rethinking the answer

Post by manmal » Tue, Dec 13, 2022, 5:13 PM UTC

pedalpete wrote: post #239

manmal wrote: post #235

Earlier quoted context omitted.

By your argument, everybody would get Alzheimer‘s sooner or later. But most old people (still) don’t.

Not necessarily. Though Alzheimer's is an age related disease, and each 5 years increases the likelihood of developing Alzheimer's [1]. The older you get, the more likely you are to get Alzheimer's. Young people don't get Alzheimer's (with the exception of early onset, which is still in an older population). So if we extend life long enough, will everyone get it? Unlikely. Just like not everyone with high cholesterol…

Post by literalAardvark » Tue, Dec 20, 2022, 10:41 PM UTC

nordsieck wrote: post #208

literalAardvark wrote: post #201

Earlier quoted context omitted.

Your interpretation is correct. I don't understand where I'm wrong about the 2x bw though? My thesis is that disregarding upper body gains, which can be compensated by other exercises, single leg squats will get you to 1x + 1x bw, which is 2x, with almost no gear at all. You can also reasonably easily add about 2x15kg in dumbbells which is almost another 0,7x or so, making home training quite powerful.

> I don't understand where I'm wrong about the 2x bw though? ... single leg squats will get you to 1x + 1x bw, which is 2x The disagreement is purely about notation. In the strength world, people routinely ignore bodyweight when measuring squat intensity - they only list load weight. I suspect that this is, in large part, an effort to be consistent with other barbell exercises like Deadlift (which I mentioned earlier…