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Canadians to start HIV vaccine clinical trials

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Re: Canadians to start HIV vaccine clinical trials

#2
Nobel peace prizes are not normally awarded to philanthropists. But I'm just going to leave this link here. It's a photo of Bill Gates with Prime Minister Stephen Harper announcing funding for HIV vaccine research in 2007.

http://pm.gc.ca/grfx/news/PM-feature-20070220-Gates.jpg

Source: http://pm.gc.ca/eng/media.asp?id=1544

Re: Canadians to start HIV vaccine clinical trials

#3
post #2

Nobel peace prizes are not normally awarded to philanthropists. But I'm just going to leave this link here. It's a photo of Bill Gates with Prime Minister Stephen Harper announcing funding for HIV vaccine research in 2007. http://pm.gc.ca/grfx/news/PM-feature-20070220-Gates.jpg Source: http://pm.gc.ca/eng/media.asp?id=1544

It is laughable to think that someone who funds research should be given an award. The people doing the actual research deserve an award leaps and bounds above and beyond the one providing funding.

Re: Canadians to start HIV vaccine clinical trials

#4
> It will test how effective the vaccine is by comparing a vaccinated and a non-vaccinated group, Kang said in the video.

So I was going to ask how clinical trials for vaccines are done, and this part kind of answers it, but now I'm curious - if there's no control group that gets a placebo injection, how do you control for the fact that people may behave differently if they think they've been given an anti-HIV vaccine? Unless I'm misreading this and "non-vaccinated" means placebo.

Re: Canadians to start HIV vaccine clinical trials

#5
post #3
post #2

Nobel peace prizes are not normally awarded to philanthropists. But I'm just going to leave this link here. It's a photo of Bill Gates with Prime Minister Stephen Harper announcing funding for HIV vaccine research in 2007. http://pm.gc.ca/grfx/news/PM-feature-20070220-Gates.jpg Source: http://pm.gc.ca/eng/media.asp?id=1544

It is laughable to think that someone who funds research should be given an award. The people doing the actual research deserve an award leaps and bounds above and beyond the one providing funding.

They are all doing a lot more than I am to fix the problem so either way, hats off to them.

Re: Canadians to start HIV vaccine clinical trials

#6
post #3
post #2

Nobel peace prizes are not normally awarded to philanthropists. But I'm just going to leave this link here. It's a photo of Bill Gates with Prime Minister Stephen Harper announcing funding for HIV vaccine research in 2007. http://pm.gc.ca/grfx/news/PM-feature-20070220-Gates.jpg Source: http://pm.gc.ca/eng/media.asp?id=1544

It is laughable to think that someone who funds research should be given an award. The people doing the actual research deserve an award leaps and bounds above and beyond the one providing funding.

I don't think you need to be so antagonistic against the funders. Not to mention that there are different awards for different things. I think it would be perfectly fine (and that all the members involved would agree) if the researchers were given the Nobel prize in Biology and the funders the Peace prize.

Re: Canadians to start HIV vaccine clinical trials

#7
Kang has been studying HIV since 1987.

This guy has been working on fighting one virus for almost 25 years. I can't quite compare what I aim to do with my startup to preventing HIV, but we certainly hope to have a massive positive impact on the world. So when I feel impatient about changing the world now, this should put things in perspective.

Re: Canadians to start HIV vaccine clinical trials

#8
post #3
post #2

Nobel peace prizes are not normally awarded to philanthropists. But I'm just going to leave this link here. It's a photo of Bill Gates with Prime Minister Stephen Harper announcing funding for HIV vaccine research in 2007. http://pm.gc.ca/grfx/news/PM-feature-20070220-Gates.jpg Source: http://pm.gc.ca/eng/media.asp?id=1544

It is laughable to think that someone who funds research should be given an award. The people doing the actual research deserve an award leaps and bounds above and beyond the one providing funding.

Why?

Not implying this is the case here, but what if the research is trivial, but requires billions of dollars?

Re: Canadians to start HIV vaccine clinical trials

#9
post #4

> It will test how effective the vaccine is by comparing a vaccinated and a non-vaccinated group, Kang said in the video. So I was going to ask how clinical trials for vaccines are done, and this part kind of answers it, but now I'm curious - if there's no control group that gets a placebo injection, how do you control for the fact that people may behave differently if they think they've been given an anti-HIV vaccin…

A couple things:

1) We generally know the strength of the placebo effect and the rate of HIV transmission among at-risk groups, so we can control for it, and

2) Not sure the placebo effect is particularly relevant. First, a vaccine that shows little to no benefit over the control (placebo or not) is not an effective vaccine. Second, placebos aren't effective for everything. I highly doubt the effectiveness of a placebo at preventing HIV transmission (although it would be difficult to test ethically).

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