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My parents, very much not South Asian, achieved the same thing as per their doctor's recommendation.
Earlier quoted context omitted.
Why would it be obvious? For that matter, since I'm out of the loop, what's the mechanism for losing fat to improve insulin control?
I thought this was common knowledge. Type 2 diabetes is 100% reversible through diet.
My parents, very much not South Asian, achieved the same thing as per their doctor's recommendation.
Yes, this has been shown in other populations already. I think the highlight of this study is that it worked in South Asians also, as some might question if genetics/ culture play a particular role. This adds to the evidence that weight loss works for diabetes in all ethnicities.
For instance African Americans have high blood pressure at an elevated rate and many of the medications that work well for other Americans don't work well for them. It's important that this population gets studies about treatments that work for them.
Isn’t this obvious?
> Isn’t this obvious? Please consider wondering why no doctors/scientist know how to heal people with diabetes. Do they miss something obvious?
>Studies with therapeutic dosing typically used very low energy diets (600-1100 kcal/day) with a weighted mean remission rate of 49.4%, while studies with subtherapeutic dosing typically used more moderate caloric restrictions (reducing energy intake by 500-600 kcal/day) and the weighted mean remission rate was 6.9%. Conclusions. Remission should be the clinical goal in T2D treatment, using properly dosed intensive lifestyle interventions as a primary component of medical care for T2D patients.[0]
So while not exactly obvious, it isn't true that "no doctors/scientist know how to heal people with diabetes." The real issue is that people with DMT2 generaly will not accept low calorie diets. But those that do have a high rate of remission and almost all have improved symptoms and decreased progressions.
Edit: I should note that obviously the American College of Lifestyle Medicine would advocate for this. My point is that there is sufficient liturature to back this up.
[0]Type 2 Diabetes Remission and Lifestyle Medicine: A Position Statement From the American College of Lifestyle Medicine (2020) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692017/?report...
There's a long history of studies showing Low-Calorie Diets as being effective for reversing T2D. The late Sarah Hallberg wrote a narrative review that I liked a lot a couple years back (see section 3.2 for the part on LCDs): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520897/ Hallberg SJ, Gershuni VM, Hazbun TL, Athinarayanan SJ. Reversing Type 2 Diabetes: A Narrative Review of the Evidence. Nutrients. 2019 Apr 1;…
The basic problem, which has been unchanged for decades, is that hardly anyone actually follows the "proper" diet on a long-term basis without some kind of surgical or drug treatment. Despite weight loss being a massive industry and a very common goal, researchers routinely struggle to find study subjects who have maintained significant long-term weight loss without medical interventions, to the point that there's a special registry to keep track of such people for scientific purposes [1].
Earlier quoted context omitted.
> Isn’t this obvious? Please consider wondering why no doctors/scientist know how to heal people with diabetes. Do they miss something obvious?
While not exactly obvious, this has been known for a while now. It even became the position statement of the American College of Lifestyle Medicine to restrict calories as a way to induce remission: > Studies with therapeutic dosing typically used very low energy diets (600-1100 kcal/day) with a weighted mean remission rate of 49.4%, while studies with subtherapeutic dosing typically used more moderate caloric restri…
I'm really confused how T2D are special such that crash dieting doesn't mess them up further and put them further in a hole. They're already messed up because of the T2D, aren't they?
Honestly, it sounds very difficult, but the doctor seemed very confident that this works. I have started trying this (not T2, but need to lose weight)
Anecdotally, a lot of people have suggested keto and low-carb diets having been successful for them.
The source was Tegus (https://www.tegus.com/) which my company had a free trial.
The general advice, even from my primary care physician, has been that anything less than 1200kcal/day is dangerous and is crash dieting. Looking around, I found this other study studying total diet replacement providing 810kcal/day as the sole food for 12 weeks, showed significantly greater weight loss compared to standard counseling and modest energy restrictions. The difference in weight loss was measured at 12 months. (BMJ 2018;362:k3760 [1])
25 BMI, which the diabetes study used in addition to T2D, is not considered clinically obese in the US. 25 BMI is the line between clinically normal and overweight. I wonder if crash dieting is advised against on the assumption that most people will go back to unhealthy eating habits instead of changing their diet, and also become more likely to fall into binge-restrict cycles. It's easy to imagine that if someone is able to make meaningful changes, crash dieting is more effective than most other methods.