It really is the appeareance of exponential curves in any field. Biology, physics, comp science, as soon as the curve appears, it amplifies the nature of those who wield it.
Comp science is obvious. Physics is similiar - if you have a working fusion device (ripped from a flying car) or any other device with exponential energy density, it amplifies the problems you can solve and cause.
Biology is harder to grasp, no not really after covid. But in theory one day not far away somebody might take a backyard shed and cook something up, which is not even a disease that has "exponential" castrophe written all over it.
Imagine a floating Lema https://en.wikipedia.org/wiki/Lemna, blue, bio engineered to harvest carbon, all good intentions, wrapped around a bubble of methan for buyoncy. Such a plant, engineered by anyone, could block out the sun.