Well there's a sense of contrition there, so that's good.
However there's no reasonable excuse. You can't be like "aw man, I wish we'd been more organized". A big piece of this is on the investors. All those depositors would have been saying "Hey Sequoia and OTPP are in there, they must have checked things are sound". Was that foolish of them, to assume reputable investors had done their due diligence? You're between a rock and a hard place when you answer this. Either they should have all done their own DD, basically not invested because who can do DD as a little guy, or large investors are not responsible for what everyone else thinks they did, which is a rather major indictment of how our financial system works.
But back to SBF's explanation. It's just juvenile, basically the same as "mommy, you didn't make me clean my room and now I slipped and hurt myself". Whatever the laws are, when someone trusts you with their money, you are responsible for certain basic things like knowing where that money is. All the money in the world and they didn't think to hire an accountant and a risk manager. Or perhaps they did and those people quietly left, we'll never know.
About the regulators, it's quite the about-turn. He goes from saying it's a good thing (which was why CZ got pissed at him?) to saying it was just PR, and that regs basically don't work anywhere. I think this is also a juvenile view. You can make the case that it often leads to unintended consequences, and that it often causes problems, but you can't sweep all regulations in all sectors into the bin, there's just too much evidence that it sometimes does work. In fact you could say that the very reinvention of finance as crypto ought to motivate participants to look at what problems were found in the financial world that were addressed by regulation. Glass-Steagal, deposit insurance, central banking, there's a lot to read about.