41–50 of 162 posts
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I hear you. Controlling your food environment is so important. It's candy on desks season again. I can usually walk past the candy, but not always.
Willpower is a finite resource indeed, you can't rely on that.
https://www.psychologytoday.com/us/blog/how-do-you-know/2020...
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We have an old, safe, cheap drug for humans already: Metformin. Most people can get an off-label metformin prescription for anti-aging or appetite suppression. Your interest in food will be reduced to the point you have trouble keeping weight on. Sugar will be repulsive to you. Sweet food tastes "sickly sweet", nauseating. Metformin also interferes with the absorption of carbohydrates in your gut.
A more appropriate drug for this is probably Ozempic/Wegovy (Semaglutide), or an even more effective version available in the US, Tirzepatide. I've personally been on the former and after 4.5 months, I've lost ~20% of my body weight
Surprisingly, metformin seems to be almost a pure win, even for healthy people: https://www.health.harvard.edu/blog/is-metformin-a-wonder-dr...
In contrast, GIP analogues like semaglutaide present real risks and are less well understood. For some people, with serious health problems, GIP analogues make sense. But generally you don't want to be taking them if you're healthy.
Earlier quoted context omitted.
We have an old, safe, cheap drug for humans already: Metformin. Most people can get an off-label metformin prescription for anti-aging or appetite suppression. Your interest in food will be reduced to the point you have trouble keeping weight on. Sugar will be repulsive to you. Sweet food tastes "sickly sweet", nauseating. Metformin also interferes with the absorption of carbohydrates in your gut.
A more appropriate drug for this is probably Ozempic/Wegovy (Semaglutide), or an even more effective version available in the US, Tirzepatide. I've personally been on the former and after 4.5 months, I've lost ~20% of my body weight
I've been hitting the gym for a few months now, and one thing that completely blew my mind was the existence of hypercalorics. Imagine that, not being able to eat a lot (specially carbs) and having to resort to these solutions. Point being, people like to spew out CICO as if fat people just don't understand thermodynamics. What I've found is that matters is appetite: some people just get full way faster than others.…
I agree that appetite is the most important factor. But I think CICO is still helpful. It's not a panacea, lots of people struggle to just eat the right amount (see appetite). But you can use CICO as a check to make sure you aren't bullshitting yourself. If you try a diet (eg. cut sugar, intermittent fasting, low carbs, etc), you will only lose weight if you have a caloric deficit. Eg. if you cut sugar from your diet…
Now imagine your body couldn't manage its own hydration properly, perhaps because we contaminated our water supplies with something that disregulates the thirst response. Then you'd have a society that spends a lot of time talking about WIWO and it'd be a pretty sick place to live. It's much healthier to treat the underlying disregulation than to force people to constantly be thirsty.
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Many foods you used to like (e.g., sweets) will be nauseating. Other foods remain delicious. For example, eggs and cheese and meat. But basically, your interest in food will be drastically reduced, and you will eat just enough. This is an important part of metformin's beneficial effect on lifespan and health.
Admittedly, I’m on a fairly low dose (500mg x 2), but I can still kill a bag of Haribo when the mood hits. It doesn’t , quite as often, but I’ve noticed no changes in flavor.
Earlier quoted context omitted.
A more appropriate drug for this is probably Ozempic/Wegovy (Semaglutide), or an even more effective version available in the US, Tirzepatide. I've personally been on the former and after 4.5 months, I've lost ~20% of my body weight
Aren’t those hard to get and then super expensive if you do quality?
I've been hitting the gym for a few months now, and one thing that completely blew my mind was the existence of hypercalorics. Imagine that, not being able to eat a lot (specially carbs) and having to resort to these solutions. Point being, people like to spew out CICO as if fat people just don't understand thermodynamics. What I've found is that matters is appetite: some people just get full way faster than others.…
Appetite differences are almost certainly the primary factor in why some people get heavy and others don't, but that isn't inconsistent with CICO at all.
Successful dieting is about managing the sensation of hunger. That’s it.
I've been hitting the gym for a few months now, and one thing that completely blew my mind was the existence of hypercalorics. Imagine that, not being able to eat a lot (specially carbs) and having to resort to these solutions. Point being, people like to spew out CICO as if fat people just don't understand thermodynamics. What I've found is that matters is appetite: some people just get full way faster than others.…
We have an old, safe, cheap drug for humans already: Metformin. Most people can get an off-label metformin prescription for anti-aging or appetite suppression. Your interest in food will be reduced to the point you have trouble keeping weight on. Sugar will be repulsive to you. Sweet food tastes "sickly sweet", nauseating. Metformin also interferes with the absorption of carbohydrates in your gut.
This may be true for some people but definitely not a universal
I've been hitting the gym for a few months now, and one thing that completely blew my mind was the existence of hypercalorics. Imagine that, not being able to eat a lot (specially carbs) and having to resort to these solutions. Point being, people like to spew out CICO as if fat people just don't understand thermodynamics. What I've found is that matters is appetite: some people just get full way faster than others.…
We have an old, safe, cheap drug for humans already: Metformin. Most people can get an off-label metformin prescription for anti-aging or appetite suppression. Your interest in food will be reduced to the point you have trouble keeping weight on. Sugar will be repulsive to you. Sweet food tastes "sickly sweet", nauseating. Metformin also interferes with the absorption of carbohydrates in your gut.
https://www.health.harvard.edu/blog/is-metformin-a-wonder-dr...
I've been hitting the gym for a few months now, and one thing that completely blew my mind was the existence of hypercalorics. Imagine that, not being able to eat a lot (specially carbs) and having to resort to these solutions. Point being, people like to spew out CICO as if fat people just don't understand thermodynamics. What I've found is that matters is appetite: some people just get full way faster than others.…
> What I've found is that matters is appetite: some people just get full way faster than others. This is a half truth. If you cut down portion size your stomach will shrink over time. I eat a lot less before feeling full now, and I only changed my life a year ago. It's also important that you eat stuff that makes you feel full, fibers and greens. Changing diet also changed my taste, so I crave more healthy things now…
Having tried this, by basically eating a lot of carrots, its uh, not the same as being full/satiated. Feeling like your stomach is full is just a completely different feeling from feeling like you ate a satiating meal.