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A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
11–20 of 162 posts
Re: A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
#12I'd love to have some help with this. I was able to drop meat, most dairy, and salty junk food without problem. I eat plenty of green leafy vegetables. But sugar. Fuuuck I cannot walk past sweets. Sugar has claws in me I cannot shake. I hope we someday understand that mechanism better, maybe enough to give me a little help.
Advice from a T2 Diabetic and regular Keto dieter.
If you have never given up sugar before, it will take at least 6-8 weeks of non-use before the cravings go away. These will be some of the hardest weeks too.
1) everything has sugar in it, and you have to absolutely avoid it, not just sweets, fruits, juices, I'd even tell you diet drinks and artificial sweeteners too. That means no ketchup, sauces, breads, and most processed and store bought foods.
2) your body will do everything to remind you about those easy access sugars. During your detox, you will have cravings, dreams about sweets, even the overwhelming urge to eat stuff you might not even thing about "oh god, i could really go for some prunes right now" sort of thing.
After your body gets it figured out that your no longer getting access to easy glucose it calms the hell down. You'll notice one day that sweets just don't seem that appealing. You'll get better at detecting sweetness in things you would have never considered sweet, like lettuce.
I warn you sugar is insidious and everywhere. One day, you will sit down to some mundane meal, nothing special about it. After a few bites, you will say, wow this is wonderful, its the best thing I have ever tasted, I absolutely must have more of this very mundane thing, I'll need seconds, thirds, more if available. That meal you were eating was loaded down with sugar, it probably didn't taste sweet but it will taste like the best thing ever. That's how sugar gets you.
Re: A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
#13I'd love to have some help with this. I was able to drop meat, most dairy, and salty junk food without problem. I eat plenty of green leafy vegetables. But sugar. Fuuuck I cannot walk past sweets. Sugar has claws in me I cannot shake. I hope we someday understand that mechanism better, maybe enough to give me a little help.
Don't drop salt, imo. It is essential for strong stomach acid (a whole system benefit), your body always ensures the salt level in the blood (and will even extract it from bones). Ask yourself - 'what is the most common medical intervention' and you will see it is a saline drip. And farmers ensure that salt is available to the their cattle for their health. And Japanese have a highly salty diet and live long, with fe…
Don't drop sugar imo
For all the similar reasons you gave, except - no sugar, no energy. You may wonder why a skinny af cyclist will happily consume 6k+ calories a day, as well as shovelling glucose gels down. Endurance athletes get it best: long distance cycling is just an all-day eating competition.
Re: A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
#14I'd love to have some help with this. I was able to drop meat, most dairy, and salty junk food without problem. I eat plenty of green leafy vegetables. But sugar. Fuuuck I cannot walk past sweets. Sugar has claws in me I cannot shake. I hope we someday understand that mechanism better, maybe enough to give me a little help.
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Re: A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
#15Just a related topic. FMT seems to cure a lot of things. I had a really really bad body odor. Doctors did not help much. It seems that during one episode in life my gut biome became really bad (heavy deinking). Years passed and nothing helped me recover from that. Various health issues also depression due to that. Latest doctor asked me to try FMT.. I was sceptic but at that point thought to myself - hell why not. An…
Had to google FMT: https://en.wikipedia.org/wiki/Fecal_microbiota_transplant
Related discussion on HN yesterday: https://news.ycombinator.com/item?id=33574568#33575598
Re: A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
#16I'd love to have some help with this. I was able to drop meat, most dairy, and salty junk food without problem. I eat plenty of green leafy vegetables. But sugar. Fuuuck I cannot walk past sweets. Sugar has claws in me I cannot shake. I hope we someday understand that mechanism better, maybe enough to give me a little help.
Advice from a T2 Diabetic and regular Keto dieter. If you have never given up sugar before, it will take at least 6-8 weeks of non-use before the cravings go away. These will be some of the hardest weeks too. 1) everything has sugar in it, and you have to absolutely avoid it, not just sweets, fruits, juices, I'd even tell you diet drinks and artificial sweeteners too. That means no ketchup, sauces, breads, and most p…
I so want to do this, but I have such a sweet tooth I don’t think I can succeed. I can go a few days without sweets but then the urge is just overwhelming. I want to try weaning, by just eating fruit instead of processed treats. Will that have any effect at all, make it harder overall, or is the only way to just cut sugar completely?
Re: A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
#17I've been hitting the gym for a few months now, and one thing that completely blew my mind was the existence of hypercalorics. Imagine that, not being able to eat a lot (specially carbs) and having to resort to these solutions. Point being, people like to spew out CICO as if fat people just don't understand thermodynamics. What I've found is that matters is appetite: some people just get full way faster than others.…
We have an old, safe, cheap drug for humans already: Metformin.
Most people can get an off-label metformin prescription for anti-aging or appetite suppression.
Your interest in food will be reduced to the point you have trouble keeping weight on.
Sugar will be repulsive to you. Sweet food tastes "sickly sweet", nauseating.
Metformin also interferes with the absorption of carbohydrates in your gut.
Re: A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
#18I'd love to have some help with this. I was able to drop meat, most dairy, and salty junk food without problem. I eat plenty of green leafy vegetables. But sugar. Fuuuck I cannot walk past sweets. Sugar has claws in me I cannot shake. I hope we someday understand that mechanism better, maybe enough to give me a little help.
Advice from a T2 Diabetic and regular Keto dieter. If you have never given up sugar before, it will take at least 6-8 weeks of non-use before the cravings go away. These will be some of the hardest weeks too. 1) everything has sugar in it, and you have to absolutely avoid it, not just sweets, fruits, juices, I'd even tell you diet drinks and artificial sweeteners too. That means no ketchup, sauces, breads, and most p…
I remember doing Keto for 3 months. Stayed under 50g carbs per day.
Lost 10kg.
But it was hard.
My "trick" was buying a Pepsi Max Cherry and a >80% chocolate, when I got cravings.
Re: A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
#19I've been hitting the gym for a few months now, and one thing that completely blew my mind was the existence of hypercalorics. Imagine that, not being able to eat a lot (specially carbs) and having to resort to these solutions. Point being, people like to spew out CICO as if fat people just don't understand thermodynamics. What I've found is that matters is appetite: some people just get full way faster than others.…
We have an old, safe, cheap drug for humans already: Metformin. Most people can get an off-label metformin prescription for anti-aging or appetite suppression. Your interest in food will be reduced to the point you have trouble keeping weight on. Sugar will be repulsive to you. Sweet food tastes "sickly sweet", nauseating. Metformin also interferes with the absorption of carbohydrates in your gut.
I once heard about one drug that basically works by making you nauseous to food. Is it the one?
> Metformin is generally safe, but common side effects do include vomiting, nausea, and diarrhea. Those experiencing these unpleasant side effects might consume less food, resulting in modest weight reductions.
Re: A gut-derived hormone suppresses sugar appetite/regulates food choice Drosophila
#20Earlier quoted context omitted.
We have an old, safe, cheap drug for humans already: Metformin. Most people can get an off-label metformin prescription for anti-aging or appetite suppression. Your interest in food will be reduced to the point you have trouble keeping weight on. Sugar will be repulsive to you. Sweet food tastes "sickly sweet", nauseating. Metformin also interferes with the absorption of carbohydrates in your gut.
I once heard about one drug that basically works by making you nauseous to food. Is it the one? > Metformin is generally safe, but common side effects do include vomiting, nausea, and diarrhea. Those experiencing these unpleasant side effects might consume less food, resulting in modest weight reductions.
Many foods you used to like (e.g., sweets) will be nauseating.
Other foods remain delicious. For example, eggs and cheese and meat.
But basically, your interest in food will be drastically reduced, and you will eat just enough.
This is an important part of metformin's beneficial effect on lifespan and health.