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Early-life low-calorie sweetener consumption disrupts memory function in rats

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11–20 of 71 posts

Re: Early-life low-calorie sweetener consumption disrupts memory function in rats

#12
post #8

> In humans, a history of habitual LCS consumption based on food-frequency questionnaires is associated with increased prospective risk for all-cause dementia. Here's a response that might make you feel better after reading that: https://www.ahajournals.org/doi/full/10.1161/strokeaha.117.0...

Not really in light of multiple other new studies indicating that they wreck insulin regulation and your microbiome. I consume them but have come to the conclusion that they are probably pretty bad in light of this new science.

> I consume them but have come to the conclusion that they are probably pretty bad in light of this new science.

That's how I feel about brown butter. It's so tasty that I don't really want to give it up entirely, but I doubt I'll consume it more than a few times a year.

Re: Early-life low-calorie sweetener consumption disrupts memory function in rats

#13
post #6

When I was in undergrad, a Cog Psych professor told me a story about an undergrad who made a poster for a regional research conference of no real consequence about the correlation between diet soda drinking and some recall task. The study and the conference were more about teaching students about research more than actually finding anything. When he and his student showed up to the conference, a representative from a…

Has there been a suspected artificial sweetener/memory issue link for a while? I could see them wanting to refute it if there were fluoride-like not very well founded concerns. Otherwise that is insanely suspicious, to the point of parody.

Re: Early-life low-calorie sweetener consumption disrupts memory function in rats

#14
post #6

When I was in undergrad, a Cog Psych professor told me a story about an undergrad who made a poster for a regional research conference of no real consequence about the correlation between diet soda drinking and some recall task. The study and the conference were more about teaching students about research more than actually finding anything. When he and his student showed up to the conference, a representative from a…

> If there is an effect, the effect size is small, and I'm not convinced there is anything there.

Even if there is, apparently sugar is doing much more damage.

Re: Early-life low-calorie sweetener consumption disrupts memory function in rats

#15
post #6

When I was in undergrad, a Cog Psych professor told me a story about an undergrad who made a poster for a regional research conference of no real consequence about the correlation between diet soda drinking and some recall task. The study and the conference were more about teaching students about research more than actually finding anything. When he and his student showed up to the conference, a representative from a…

I guess it's good that the sugar industry has enough money to fund studies of artificial sweetener and vice versa.

Re: Early-life low-calorie sweetener consumption disrupts memory function in rats

#17
post #8

Earlier quoted context omitted.

Not really in light of multiple other new studies indicating that they wreck insulin regulation and your microbiome. I consume them but have come to the conclusion that they are probably pretty bad in light of this new science.

> I consume them but have come to the conclusion that they are probably pretty bad in light of this new science. That's how I feel about brown butter. It's so tasty that I don't really want to give it up entirely, but I doubt I'll consume it more than a few times a year.

What's wrong with brown butter?

Re: Early-life low-calorie sweetener consumption disrupts memory function in rats

#18
post #8

> In humans, a history of habitual LCS consumption based on food-frequency questionnaires is associated with increased prospective risk for all-cause dementia. Here's a response that might make you feel better after reading that: https://www.ahajournals.org/doi/full/10.1161/strokeaha.117.0...

Not really in light of multiple other new studies indicating that they wreck insulin regulation and your microbiome. I consume them but have come to the conclusion that they are probably pretty bad in light of this new science.

But is this really science? What they did was garden variety P-hacking. IMO that calls into question the entire conclusion, which means don't use it to confirm things heard elsewhere.

Nutritional science is hard. We either do it on animals and get results that may not apply to humans, or we do observational studies that rely heavily on self-reporting and extended timelines, with dubious value as a result. We can't do the same kinds of experiments ethically on humans that we're okay with doing on animals.

Re: Early-life low-calorie sweetener consumption disrupts memory function in rats

#19
post #9

Aspartame and probably all the other artificial sweeteners are small molecules. All small molecules have the potential for drug-like interactions with biological processes. I would expect that in most cases at small doses the body can maintain homeostasis, but caution is still warranted. More generally, It’s a reasonable heuristic to avoid foods that can’t be prepared without industrial chemistry. For example, I can’…

What oils are not derived from seeds? Olive, Avocado, Canola, Safflower, Corn...All of these are seeds. Are you saying that we should not use vegetable oils? Just use butter / lard / tallow?

Am I missing something?

Re: Early-life low-calorie sweetener consumption disrupts memory function in rats

#20
post #17

Earlier quoted context omitted.

> I consume them but have come to the conclusion that they are probably pretty bad in light of this new science. That's how I feel about brown butter. It's so tasty that I don't really want to give it up entirely, but I doubt I'll consume it more than a few times a year.

What's wrong with brown butter?

Studies and headlines on media come out every so often linking burned/browned foods to cancer, and likewise comes every so often a meta analysis stating the contrary.

Heck, until the writing of this comment, I thought that browned foods increased cancer risk but were in the category of "we all have to die of something" because I wasn't giving them up.

BBC saying toast will kill you: https://www.bbc.com/news/health-38680622

Meta analysis discrediting the idea: https://pubmed.ncbi.nlm.nih.gov/25403648/

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