Earlier quoted context omitted.
On Windows, when you Copy the program supplying the data decides whether to send the data to the clipboard manager straight away, or whether to defer. If it defers, then yes it does a "last call" on closing. If it crashes you lose the clipboard. Some programs will ask you when you quit them if you want to keep the clipboard contents, if you'd copied a large amount of data.
Annoyingy, in Excel's case that question "Do you really want to quit? You have copied large amounts of data to the clipboard." even occurs when you have a single cell's worth in the clipboard. But that's also a confirmation question that no one really understands unless they understand how the clipboard works (or can work).
That's not correct. You need to have quite a few cells in the clipboard for this to happen.
> But that's also a confirmation question that no one really understands
The dialog tells you exactly what it is asking for. It gives you three options: keep the app open, store the data in the clipboard, discard the data from the clipboard. I am not sure how a user could not understand what to do in that situation.