Scary thing is how many people don't consider this to be scary.
If we were to blame anyone, we should blame ourselves. But I'll return to that in a moment.
We live in a complex system, so we can blame the political/financial system for providing wrong incentives, loans and subsidies to the big agriculture, based on profitability alone.
We can blame agriculture companies for sprayng millions of tons of poisons all over our countryside to keep profits up and costs down. When you're planting monocrops, and spraying it with pesti/herbicides, you're propagating environmental equivalents of deserts. Deserts leaking poisons not only on itself, but through whole nature (through wind & water cycle).
Both pesticides and herbicides are inbelievably poisonous not only to plants and pests, but also to other bugs (we all know at least about bees), to all other animals, the animals we feed with the produce, and in the end, even to humans. Those poisons' bioaccumulate and their neurodegenerative and hormons-altering effects are causing havoc not only in bugs, frogs and mice, but also in humans (parkinson, etc.).
The solution is something we're actively killing with our current agricultural practices. Biodiversity.
For example, we don't need to kill the mice with poisons. We can interplant trees into our fields to provide living space for predators (e.g. owls and foxes) to manage the mice population and not use the poisons to keep those predators alive.
We can't reasonably expect the return of an army of small farmers, providing local communities with poison-free grown food, not in a reasonable time frame we have until environmental collapse and/or extinction of key animal kinds (no pollinators, no birds, no small predators, more mice, more bad bugs and diseases, famines ...).
But what we can do, we can change our habits. We don't have to eat meat/dairy, which is incredibly land/resource/poison intensive (we would need 4+ earths to feed the world's population same diet as americans have). We don't have to feed other animal 20x more food than we would need only to eat its muscles. We don't have to cut down forests to grow meat (we would need 1/4 of the land to feed the population if everybody were to switch to a plant based diet), if we eat the plants ourselves and let the nature be and let it repair itself.
We can then change the political/financial/agricultural system through our own actions (buying/cooking/eating). When enough people do, there won't be the pressure to produce a much as we currently do, then we can legislate the change in the agriculture , forbid use of poisons, protect the ecosystems, reforest the earth, live in sync with the nature, stop exploiting everything (and living beings) with our need for financial gains.
Sorry for my bad english. Also, I'm in the system, it's monday, no time to write shorter comment, and no time to incorporate everything-that-is-wrong and everything-that-should-be-done. It's a complex system. But it can be solved in our own kitchens.