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Most people on antidepressants don’t need them

economist.com

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Re: Most people on antidepressants don’t need them

#21
Statements like this need to be worded very carefully. In many people's minds, saying something like "most people don't need antidepressants" quickly becomes "antidepressants are useless". Many people who may benefit from them get scared away.

Speaking as someone who has been on/off antidepressants for GAD+OCD for the better part of a decade, I've had countless people tell me that antidepressants are useless and just placebo pills pushed by Big Pharma. But for me, they are life changing. They turn me from someone who just sits indoors having panic attacks all day to someone who can live a relatively normal life. I've tried (and continue to have) therapy, but SSRIs are wonder drugs for myself and many other people.

The caveat is, you often need to try 2 or 3 different SSRIs before you find one that works for you, and if you're unlucky, you may not find one, or the side effects can be intolerable. For me, I tried fluoxetine and citalopram, neither of which really worked, but sertraline changed everything almost overnight. The only side effect I've experienced is weight gain, which isn't great, but is better than the alternative.

However, this is the UK which may have a different attitude to the drugs. Before and during initial treatment, I was provided with around 20 behavioural therapy sessions, and even now I still have quarterly drug reviews with a doctor. At no point did I feel like I was being pushed onto SSRIs, and they checked to make sure it wasn't something environmental that could be easily remedied before asking if I would like to consider medication.

Re: Most people on antidepressants don’t need them

#24

I can tell this thread is going to be a nightmare but whatever I really want to share my experience in case there are people similar to me that need to hear this: I cannot emphasise enough how much Escitalopram (lexapro) has helped me with issues I didn't even know I had until I started taking it. At which point I realised I was living in a constant state of anxiety up to that point, and I probably should have been o…

Me too! I used to be anxious about everything going on in my life. When I started Lexapro and it finally started working, I realized, "Wow, is that what normalcy feels like?" It's been a lifesaver.

I also used to have general, ever present anxiety, but never was medicated for it. It seems to have abated by around age 29 to a large extent.

One thing that helped was finding a group of friends who loved and accepted me as I was. Really a key moment in dealing with the social component of anxiety.

I think pharmaceutical intervention and my path are both valid, but it's way harder to prescribe "friends who love you in the right way."

Re: Most people on antidepressants don’t need them

#26
post #2

You could probably swap "antidepressants" for any number of drugs and it's still a true statement.

I think antidepressants are getting the spotlight because some (many) were approved with only a slim I get the feeling that drug approval laxed for a good while and let these slip through [1] https://pubmed.ncbi.nlm.nih.gov/17264159/

I'm not sure how universal this is, but for me, phenylephrine is literally just side effects. It still makes my anxiety worse, but does nothing for my congestion.

Re: Most people on antidepressants don’t need them

#27
I went through a phase in my life a few years ago where I tried most antidepressants available in my European country. All were prescribed to me at varying doses by a psychiatrist working in our public health system.

Almost every single antidepressant gave me withdrawal symptoms (extremely intense mood swings and brain zaps) when I tried decreasing the dose. I mentioned this to my psychiatrist, who advised me to split the pills in order to slowly decrease the dosage. Even splitting the pills and taking a quarter of a pill less every 2 weeks was giving me withdrawal symptoms. I resorted to carefully dissolving the medication in water and volumetrically dosing to get the right rate of tapering off. This scenario happened to me with both Sertraline and Fluoxetine. The "newer" antidepressants like Escitalopram and Vortioxetine gave me less withdrawal symptoms, but they also had more severe side-effects whilst on the medication. Obviously this is all anecdotal, but my hope is that doctors would put greater emphasis on the possible adverse effects of antidepressants to patients. No other class of medication has been so... rough? for me. Glad to be medication-free now.

Re: Most people on antidepressants don’t need them

#28
post #9

I'm a bit nervous about these articles clearly centred on the USA which seems to have an epidemic of private drug companies pushing all kinds of stuff via doctors who may or may not be getting backhanders to push certian drugs. I'm not saying this isn't partially true in Europe but the USA definitely comes across as choosing drugs as the first resort for many things that you wouldn't in Europe. Also, as many have fou…

Here are some OECD stats:

https://en.wikipedia.org/wiki/List_of_countries_by_antidepre...

here is that data with US included: https://www.businessinsider.com/countries-largest-antidepres... (tho i am not sure i would trust BI with anything..)

Certainly seems relevant to quite a few european countries. And even more relevant to developing countries to not follow us in that way..

Re: Most people on antidepressants don’t need them

#29
post #20

I was about to write that there clearly are huge differences betwween the US and the rest of the world, but it seems some European countries have caught up with the US, especially Iceland, with more than 140 daily doses per 1000 adults [1]. Interestingly Iceland frequently has one of the top positions in the world happiness report [2]. [1] https://en.wikipedia.org/wiki/List_of_countries_by_antidepre... [2] https://en…

Aren't areas near North Pole dealing with more seasonal depression due to lack of light in winter months?
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