I can tell this thread is going to be a nightmare but whatever I really want to share my experience in case there are people similar to me that need to hear this: I cannot emphasise enough how much Escitalopram (lexapro) has helped me with issues I didn't even know I had until I started taking it. At which point I realised I was living in a constant state of anxiety up to that point, and I probably should have been o…
Most people on antidepressants don’t need them
11–20 of 167 posts
Re: Most people on antidepressants don’t need them
#12It's a line of reasoning that is technically true but really sort of missing the point.
The problem with treating depressed people is to get them to actually do the things that will help them. That can be incredibly difficult without medication.
Re: Most people on antidepressants don’t need them
#13I can tell this thread is going to be a nightmare but whatever I really want to share my experience in case there are people similar to me that need to hear this: I cannot emphasise enough how much Escitalopram (lexapro) has helped me with issues I didn't even know I had until I started taking it. At which point I realised I was living in a constant state of anxiety up to that point, and I probably should have been o…
I lived like that for 15 years :(
Re: Most people on antidepressants don’t need them
#14It's unclear what paper they refer to, as it is not linked. This article (https://www.ncbi.nlm.nih.gov/books/NBK361016/) has many citations to papers that cover this stuff. I think the important take away is in "Antidepressant drug effects and depression severity: a patient-level meta-analysis" (https://pubmed.ncbi.nlm.nih.gov/20051569/):
"Results: Medication vs placebo differences varied substantially as a function of baseline severity. Among patients with HDRS scores below 23, Cohen d effect sizes for the difference between medication and placebo were estimated to be less than 0.20 (a standard definition of a small effect). Estimates of the magnitude of the superiority of medication over placebo increased with increases in baseline depression severity and crossed the threshold defined by the National Institute for Clinical Excellence for a clinically significant difference at a baseline HDRS score of 25.
Conclusions: The magnitude of benefit of antidepressant medication compared with placebo increases with severity of depression symptoms and may be minimal or nonexistent, on average, in patients with mild or moderate symptoms. For patients with very severe depression, the benefit of medications over placebo is substantial. "
Short version: if your depression is mild, antidepressants may not work better than a placebo (though placebos are not exactly nothing). If it's severe, there is more of a chance it'll really help,
From my personal experience, I can definitely attest to them helping, though they are not by any means a magic bullet.
Re: Most people on antidepressants don’t need them
#15I can tell this thread is going to be a nightmare but whatever I really want to share my experience in case there are people similar to me that need to hear this: I cannot emphasise enough how much Escitalopram (lexapro) has helped me with issues I didn't even know I had until I started taking it. At which point I realised I was living in a constant state of anxiety up to that point, and I probably should have been o…
So chalk that up as another Lexapro win (that was not forced by some drug company on the patient).
Re: Most people on antidepressants don’t need them
#16I can tell this thread is going to be a nightmare but whatever I really want to share my experience in case there are people similar to me that need to hear this: I cannot emphasise enough how much Escitalopram (lexapro) has helped me with issues I didn't even know I had until I started taking it. At which point I realised I was living in a constant state of anxiety up to that point, and I probably should have been o…
Re: Most people on antidepressants don’t need them
#17I can tell this thread is going to be a nightmare but whatever I really want to share my experience in case there are people similar to me that need to hear this: I cannot emphasise enough how much Escitalopram (lexapro) has helped me with issues I didn't even know I had until I started taking it. At which point I realised I was living in a constant state of anxiety up to that point, and I probably should have been o…
Re: Most people on antidepressants don’t need them
#18I'm a bit nervous about these articles clearly centred on the USA which seems to have an epidemic of private drug companies pushing all kinds of stuff via doctors who may or may not be getting backhanders to push certian drugs. I'm not saying this isn't partially true in Europe but the USA definitely comes across as choosing drugs as the first resort for many things that you wouldn't in Europe. Also, as many have fou…
Re: Most people on antidepressants don’t need them
#19Re: Most people on antidepressants don’t need them
#20[1] https://en.wikipedia.org/wiki/List_of_countries_by_antidepre...
[2] https://en.wikipedia.org/wiki/World_Happiness_Report#2022_Wo...