> or some wiser developer refactors substantial parts of the interface, business logic, persistence, and runtime configuration, effectively creating a framework within that application
That's not what people commonly understand as a "framework". Nor is it a helpful definition because then where does "abstracting things" and "framework" start and end?
No, the main difference between frameworks and what you describe is the IOC. In the framework world, the framework calls you and then something happens behind the scenes until the framework decides to call some code that you provided via the frameworks API.
With libraries it's the other way around: you call the library and then you do something with the result and then use it to call the library again and so on until you have the desired outcome.
The difference is, for example, that you can call the library and when it returns something to you, you can inspect it and choose to ignore it. You can do so in an arbitrary way. In the framework case, if the framework does not provide any way for you to interact with it in the way you want, then you are screwed.