It just means you're not doing anything interesting on your job.
If you have constraints, i.e. not enough compute, not enough memory, not enough storage, then you'll need a solution and, odds are, somebody has had the same problem before and it's been written up already in Knuth's TAOCP. Of course, the problem won't be exactly in the form it's been written up, but you have to have enough experience and knowledge to know the abstract form of your problem in order to figure out what parts of TAOCP would be useful to you.
Want a concrete example? Well, I'm in the generation that go to assume that storage was basically constant access regardless of whether you wanted to access the 1st byte, or the Nth one. New, high-performance memory like NAND flash, is weird because it's fundamentally unreliable. In order to make NAND reliable you have to do stuff, and some of the stuff you can do, makes NAND look like tape, and accessing tape is best done sequentially. Guess what TAOCP has? All these great ideas about maximizing random access to sequential media.