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Mouse embryo with brain and beating heart created from stem cells

cambridgeindependent.co.uk

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Re: Mouse embryo with brain and beating heart created from stem cells

#11

Post by pyuser583 »

biolotthek wrote: post #5

> to understand why so many pregnancies fail and how we might be able to prevent that from happening Are we sure that's a good idea? I've read that one of the reason for early pregnancy failure is that the embryo is not fit enough and it would be a waste of time and resources to commit to it. Another very counterintuitive finding is that if you try to implant embryos in various tissues (brain, liver, ...), the one in…

That might be true, but I know for a fact it’s a truism that doctors tell women to not feel as bad about miscarriages.

My wife has had multiple miscarriages, to the point where it’s expected. Until doctors are informed of her history, they always say “the embryo wasn’t healthy enough to survive on its own …”

My wife has a number of hormonal issues, but doctors can’t find a single diagnosis.

But it’s certainly not weak embryos.

Re: Mouse embryo with brain and beating heart created from stem cells

#13

Post by colechristensen »

shash wrote: post #7
biolotthek wrote: post #5

> to understand why so many pregnancies fail and how we might be able to prevent that from happening Are we sure that's a good idea? I've read that one of the reason for early pregnancy failure is that the embryo is not fit enough and it would be a waste of time and resources to commit to it. Another very counterintuitive finding is that if you try to implant embryos in various tissues (brain, liver, ...), the one in…

The question is why is the embryo not “fit enough”. One way to increase the chance of success is by making the embryo “more fit”, but that requires an understanding of what that definition of fitness is, and that is what I understand this study is about.

The genetic recombination process often results in failure, shuffling genes around and associated mutations breaks important things and the embryo gets to the point where it can no longer survive. It is sort of the first filter in evolution, surviving the single-cell to infant process.

Re: Mouse embryo with brain and beating heart created from stem cells

#15

Post by fsckboy »

gardenfelder wrote: post #2

This really is pretty amazing work. But, to the uninitiated, there's a dark side; I overheard someone commenting about an earlier post about this experiment, thinking it's possible to get out a chemistry set and just make a living thing. To be clear, they started with stem cells, and teased them into doing the right thing - they did not create a new living artifact from scratch; > Instead, they used stem cells - the…

> to the uninitiated, there's a dark side

to the initiated I wish there was a dark side!

> they did not create a new living artifact from scratch

that is where this is headed, that is where they want to go, that is not what they've done... till they do it. That is the dark side. Humans in a competition with one another are not capable in a broad sense of reining in every worst impulse, as we saw with recent "gain of function" experiments.

Re: Mouse embryo with brain and beating heart created from stem cells

#16

Post by anon_123g987 »

biolotthek wrote: post #5

> to understand why so many pregnancies fail and how we might be able to prevent that from happening Are we sure that's a good idea? I've read that one of the reason for early pregnancy failure is that the embryo is not fit enough and it would be a waste of time and resources to commit to it. Another very counterintuitive finding is that if you try to implant embryos in various tissues (brain, liver, ...), the one in…

No post body was provided.

Re: Mouse embryo with brain and beating heart created from stem cells

#17

Post by bpodgursky »

anon_123g987 wrote: post #16
biolotthek wrote: post #5

> to understand why so many pregnancies fail and how we might be able to prevent that from happening Are we sure that's a good idea? I've read that one of the reason for early pregnancy failure is that the embryo is not fit enough and it would be a waste of time and resources to commit to it. Another very counterintuitive finding is that if you try to implant embryos in various tissues (brain, liver, ...), the one in…

Quoted post unavailable.

The OP posted an entirely mainstream hypothesis. Let's not gatekeep and rely on credentialism.

Re: Mouse embryo with brain and beating heart created from stem cells

#19

Post by TEP_Kim_Il_Sung »

cirrus3 wrote: post #12
rossdavidh wrote: post #4

"Elsewhere on campus, two other Cambridge scientists created a non-synthetic embryo with brain and beating heart, baby shower scheduled for mid-2023."

Quoted post unavailable.

No post body was provided.

Re: Mouse embryo with brain and beating heart created from stem cells

#20

Post by TEP_Kim_Il_Sung »

shash wrote: post #7
biolotthek wrote: post #5

> to understand why so many pregnancies fail and how we might be able to prevent that from happening Are we sure that's a good idea? I've read that one of the reason for early pregnancy failure is that the embryo is not fit enough and it would be a waste of time and resources to commit to it. Another very counterintuitive finding is that if you try to implant embryos in various tissues (brain, liver, ...), the one in…

The question is why is the embryo not “fit enough”. One way to increase the chance of success is by making the embryo “more fit”, but that requires an understanding of what that definition of fitness is, and that is what I understand this study is about.

No post body was provided.
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