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Ask HN: What interesting problems are you working on?

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Re: Ask HN: What interesting problems are you working on?

#262
post #6

A little while ago, a patent for high throughput DNA synthesis using silicon chips went off-patent, so I have been learning analog IC chip design to build an open source high-throughput DNA synthesis chip. If it works, and I sold them at cost, it would reduce the cost of oligo pool synthesis by ~100x and possibly gene synthesis by 10x. For about 8-9 years now my goal has been to build a cell from scratch for less tha…

How will you prevent people from using this technology to create DIY pathogens? If the answer is "I won't" or "it'll be open source, I won't be able to", consider doing something less harmful instead.

Presumably the answer is "do exactly what is done now", which is to say offer the tech as a service (i.e. don't sell the hardware) and screen the uploaded sequence requests for dangerous sequences.

Re: Ask HN: What interesting problems are you working on?

#263
post #225

Working on a better solution to sedentary health and sitting caused back pain at work. No one posture is the answer, so there is probably an optimal amount of regular postural variation during deskwork that wouldn't interrupt focus. That is what a chair should do for you to protect your health, so making a smart dynamic chair for standing desks. Had a cycling accident years ago, became much more sitting intolerant af…

This is a great idea. On a related note I just read this ~2000s article[0] by an anthropologist about natural sleeping/resting positions amongst humans/primates. An interesting take he had was that having the chest firmly on the ground during sleep was ideal because breathing causes constant motion of your spine and prevents stiffness. [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1119282/

Interesting, that fit's one of the lines of research on disc health because the disc are nourished indirectly mostly through the porous vertebrae, it takes motion to create the pressure variations to facilitate blood flow. This may be why most active chairs don't move the needle enough, the motion is both limited and usually only triggered when a person is prompted to move by discomfort.

Re: Ask HN: What interesting problems are you working on?

#264
I'm having a blast working on https://printnanny.ai/ - the embedded computer vision system is cool, plus there are many meaty unsolved problems in the 3D printing universe. To name a few...

- Rolled a Linux distribution (PrintNanny OS) designed for mixing/matching controller software across a manufacturing "fleet".

- Created an atomic upgrade/rollback system.

- Built a WebRTC stack for live camera streaming.

- Lots of fun applying queue theory to distribute work across a fleet.

I'm learning a lot about how the government contract/bid process works, which I've always been insulated from as an engineer (even when working at companies known for gov support, like Red Hat).

My biggest customers tend to serve an ultra-specific niche, which is always fun to learn about. I love getting to talk to people who have spent thousands of hours cracking the laser tag gun market in Canada, or top RV parts supplier in Pacific Northwest, etc. There are entire worlds-within-worlds out there. =)

Re: Ask HN: What interesting problems are you working on?

#265
post #246
post #218

Earlier quoted context omitted.

What makes this different from Focusmate.com?

Great question! Focusmate is a great product centered around virtual co-working and work productivity, whereas Double will not be centered around co-working, but for everyday tasks (which can include co-working). As a result, we are designing the experience to be tailored towards the everyday experiences rather than a co-working product used for everyday task. Essentially, we want to expand the scope of tasks you can…

Nice, afaik focusmate is used for every day tasks, but not much. What do you want to do different? I Used focusmate for a week or so but It stopped helping me at all once novelty wore off ( same as every adhd/ procrastination tool yet)

Re: Ask HN: What interesting problems are you working on?

#266
post #248

A new platform to play Magic: The Gathering digitally. Been working on it since the pandemic started. It's almost done. It's a multiplayer sandbox (no rules enforcement) that just allows you to play by providing all the different zones the game involves (play area, hand, lib, gy, ex) and letting you free-drag between them. It has features for every mechanic the game involves - tapping, turning face-down, switching ca…

this reminds me a bit of Cockatrice - hope your version ends up cooler though!

Yep, Cockatrice is one of those old-fashioned options I'm trying to improve on :)

Re: Ask HN: What interesting problems are you working on?

#267

Working on kafka clone in golang. Currently adding consumer groups.

would be interested to contribute if its open source

Still early stages but building on top of this. - https://github.com/travisjeffery/jocko

Since, the author has moved onto other projects. decided it would be an interesting challenge

Re: Ask HN: What interesting problems are you working on?

#268

Academic and Scientific publishing. It's the primary source material of human knowledge. It should be completely open and accessible to everyone with no barriers to access the literature or to add to the literature. The structure it currently takes - academic journals - made perfect sense in the 1600s when that structure was developed, and it continued to work reasonably well for distributing academic results up into…

I’ve been interested in building a similar platform for quite some time. I actually bought the scholar.io domain for that purpose, but never got around to it.

Re: Ask HN: What interesting problems are you working on?

#269
post #202

Trying to teach myself linear algebra and deep learning so I can apply it to some interesting ideas I have about making current chess AI much stronger. I don't want to reveal too much since I don't want some Stockfish dev to steal my idea but I'm interested in tips and resources on linear algebra. I always hated matrices... Interspersed with that I have a huge amount of stuff to implement for my project still(search…

I'm actually in a similar boat learning these things to apply to chess but rather than making a stronger AI, trying to learn and catalog strategies to make learning chess more intuitive. Would be interested in talking more if you are! Can message me on lichess.org/@/v8xi if you play there

That's a really interesting and sorely needed niche! I originally started out thinking about this, but the only ideas I could come up with were strength related, so I switched directions.

Today's engines are hard if not impossible for amateur players to use correctly. I sent you a message on lichess!

Re: Ask HN: What interesting problems are you working on?

#270

I'm having a blast working on https://printnanny.ai/ - the embedded computer vision system is cool, plus there are many meaty unsolved problems in the 3D printing universe. To name a few... - Rolled a Linux distribution (PrintNanny OS) designed for mixing/matching controller software across a manufacturing "fleet". - Created an atomic upgrade/rollback system. - Built a WebRTC stack for live camera streaming. - Lots o…

Pretty interesting. Have you worked with existing manufacturers that do this like BambuLab?
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