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Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

theguardian.com

11–20 of 103 posts

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#11

We seem to be getting a lot of "wake up calls" but no one ever seems to answer the god damn phone.

Seeing how a large portion of the population have never used a wake up call as a service, they just think it is some rude telemarketer calling that just gets added to the block list. Problem solved

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#12
post #7

Before getting too excited about the experimental prevention they used, IL-1B blockade, let me say that blocking the innate immune system to prevent cancer seems ill-advised. The innate immune system is with us for very good reasons. This would be roughly equivalent to preventing table saw accidents by prophylactically removing all fingers. Yes, table saw accidents are terrible, but there is a straightforward electro…

Well I read the article and got excited about eliminating internal combustion engines...

https://www.brusselstimes.com/news/business/145130/fine-part...

That won't necessarily solve this problem.

[edit] One more source. There are tons though. https://www.oecd-ilibrary.org/sites/4a4dc6ca-en/index.html?i...

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#13
post #10
post #5

Earlier quoted context omitted.

The other thing people don’t often talk of is PM2.5 inside their home while cooking. Lot of people have poor ventilation or insufficient air movement capacity in their kitchens.

From the food, or the fuel?

A lot of it is from the natural gas combustion, but the food itself also contributes. The day I got an air quality sensor (to assess risk from wildfire smoke), I realized that my kitchen is basically an asthma factory for the kids. (I haven't actually assessed the risk from that, as its different from wildfires smoke, but j just keep the kids out of the kitchen now until the air clears)

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#14

Didn’t we know this in the 1970’s?

The news here is not that air pollution is linked to cancer, but about what the underlying mechanism could be:

> "However, the biological basis for how air pollution causes cancer has remained unclear. Unlike smoking or sun exposure, which directly cause DNA mutations linked to lung and skin cancer, air pollution does not cause cancer by triggering such genetic changes."

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#15
post #3

Earlier quoted context omitted.

I wonder how important the raw amount of emissions is. Density should decrease at a cubic rate of distance, so being close to a small source of emissions might be worse than being somewhat far from a heavier source.

See for yourself. Propublica plotted a "cancer map" of elevated cancer risks, and you can see how it drops off as you go away from certain points. https://projects.propublica.org/toxmap/

Interesting. One question totally non-sequiter to the toxicity conversation, but why do people that use maps orient the image in a direction other than North being up so that they have to add a label to the image indicating the direction of North?

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#16
post #7

Earlier quoted context omitted.

Well I read the article and got excited about eliminating internal combustion engines...

https://www.brusselstimes.com/news/business/145130/fine-part... That won't necessarily solve this problem. [edit] One more source. There are tons though. https://www.oecd-ilibrary.org/sites/4a4dc6ca-en/index.html?i...

Exactly right, tire and brake dust are still awful with EVs, though contra the slight implication in the headline, it's no worse than the current situation with ICE vehicles. And the brake dust aspect may slightly reduce due to regenerative braking.

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#17
post #5
post #2

I wanted to find an account of what the biggest sources of PM2.5 are in the US. This article discusses traffic fumes (24% of PM2.5), but I was surprised to learn that by far, the largest source of PM2.5 - 45% - is “unspecified sources of human origin.” Where does that stuff come from? Well, it’s created in the atmosphere via secondary reactions between agricultural NH3 emissions, SO2 and NOx emissions from shipping a…

The other thing people don’t often talk of is PM2.5 inside their home while cooking. Lot of people have poor ventilation or insufficient air movement capacity in their kitchens.

Getting an air quality monitor during covid really blew my mind when I saw the amount cooking pollution and how long it can linger. No one should be cooking inside without a vent running or a window open.

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#18

Didn’t we know this in the 1970’s?

Yeah, PM2.5 is listed as a known carcinogen, and there is strong epidemiological data supporting the link between respiratory tract cancers and pollution.

This work provides a mechanism for how this happens, where air pollution promotes the transition of cells into a malignant state, without directly damaging DNA.

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#19

Earlier quoted context omitted.

https://www.brusselstimes.com/news/business/145130/fine-part... That won't necessarily solve this problem. [edit] One more source. There are tons though. https://www.oecd-ilibrary.org/sites/4a4dc6ca-en/index.html?i...

Exactly right, tire and brake dust are still awful with EVs, though contra the slight implication in the headline, it's no worse than the current situation with ICE vehicles. And the brake dust aspect may slightly reduce due to regenerative braking.

"Electric vehicles are estimated to emit 5-19% less PM10 from non-exhaust sources per kilometre than internal combustion engine vehicles (ICEVs) across vehicle classes. However, EVs do not necessarily emit less PM2.5 than ICEVs. Although lightweight EVs emit an estimated 11-13% less PM2.5 than ICEV equivalents, heavier weight EVs emit an estimated 3-8% more PM2.5 than ICEVs"

So. It depends. It's sometimes slightly better, sometimes slightly worse. But it doesn't really solve the issue.

Re: Cancer breakthrough is a ‘wake-up’ call on danger of air pollution

#20
I know essentially nothing about this topic, but it seems likely that some particles are more dangerous than others (though I've seen no suggestion of that). I'd prefer to go after the elephants in the room before the hamsters.

There are MULTITUDES of particles in circulation everywhere everyday. If the impact of only some these are especially dire, we should be able to triage each particle simply by: 1) looking at who suffers most from 'lung cancer of unknown etiology' and what environmental particles they were exposed to, and to a lesser extent, 2) looking at who is exposed to each type of particle and whether they suffer from it.

It'd be nice if we had some clear hypotheses in mind before charging off in all directions.

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