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Is early-onset cancer an emerging global epidemic?

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Re: Is early-onset cancer an emerging global epidemic?

#151

Post by verall »

lambdaba wrote: post #62
candiddevmike wrote: post #34

Earlier quoted context omitted.

Autophagy keeps getting brought up with such pseudoscientific bullshit explanations that I can't help but see it as snake oil. Furthermore, depending on who is describing it, the window for autophagy to kick in is anywhere from 8-48+ hours.

I don't know what science you need to understand a system that is constantly active and is never fully allowed to rest will develop dysfunction. Anyway, as the sibling reply says, there is plenty of reputable research available to satisfy your curiosity if you wish.

This is not necessarily a given, depending on the nature of the system, it absolutely requires evidence.

Does my circulatory system need to fully rest so as not to develop dysfunction?

Re: Is early-onset cancer an emerging global epidemic?

#152

Post by Broken_Hippo »

coenhyde wrote: post #139
blablabla123 wrote: post #121

Earlier quoted context omitted.

But I also think "back in the days" life was more fixed. Probably getting a full time job as employee, starting a family, getting a house was not really optional. Now there are much more choices. Add to that all the hyper-connectivity. I don't really think people were better off but were just forced to handle everything more calmly. Growing up in the 90s, what I've found is that things changed a lot when people were…

Not to mention living in America is like playing life on hard mode; at least relative to other OECD countries. There's a lot more things you have to take care of / think about in America. There's a level of mental overhead that does not exist in other developed countries that many Americans do not realize are optional. eg health insurance, education, unemployment safety net, or even little things like way too many co…

There's a level of mental overhead that does not exist in other developed countries that many Americans do not realize are optional. eg health insurance, education, unemployment safety net, or even little things like way too many coverage options when buying car insurance.

I occasionally try to stress how these things seriously improve living standards. Just health insurance itself does a great deal to eliminate stress. I can go and get a weird mole checked out. I can get an MRI when I've been having headaches to make sure it isn't cancer. I can get the spot on my pancreas scanned every 6-12 months to make sure it doesn't do weird stuff. All for less out of pocket than $300 per year and my taxes are less than state + federal + premiums.

Re: Is early-onset cancer an emerging global epidemic?

#153

Post by thebigspacefuck »

vermilingua wrote: post #44
dr_hooo wrote: post #24

Earlier quoted context omitted.

Sorry, but are we supposed to get this reference, or start Googling for math professor cancer?

Ted Kaczynski

That’s what I thought originally but he wasn’t ever professor at Harvard and he was in his 50s in the 90s so it must be someone else.

Re: Is early-onset cancer an emerging global epidemic?

#154

Post by graaben »

mihaic wrote: post #140

Anecdotally, I've found out in recent year about many women having serious thyroid issues. I'm sure more people being open about their health increases this, but the sheer frequency seems absurd. Whatever industrial chemicals we're ingesting need to be drastically controlled, and this poisoning needs to be branded so that the general population knows about it. I don't want years of my life to be an externality to a s…

My wife (early 30s) was recently diagnosed with thyroid cancer and it's been absolutely shocking to hear how many other young women just in our social circle have also had it.

Re: Is early-onset cancer an emerging global epidemic?

#156

Post by WFHRenaissance »

haldujai wrote: post #148
photochemsyn wrote: post #49

> "However, the effects of individual exposures remain largely unknown. To study early-life exposures and their implications for multiple cancer types will require prospective cohort studies with dedicated biobanking and data collection technologies." What that means is analytical body-burden data collection should be a medical norm, for a variety of substances: polychlorinated biphenyls, triazine herbicides (atrazin…

It would be nice to have this information to see if any trends are discovered (all of this is theoretical, I question whether measuring excreted compounds rather than stores is is relevant but that’s a separate point) however it is unclear what value this information will provide and seems unlikely it will generate anything actionable. With that in mind, it’s hard to justify the colossal costs that would be involved…

> Young (Tell this to my mom.

Re: Is early-onset cancer an emerging global epidemic?

#157

Post by Gatsky »

photochemsyn wrote: post #49

> "However, the effects of individual exposures remain largely unknown. To study early-life exposures and their implications for multiple cancer types will require prospective cohort studies with dedicated biobanking and data collection technologies." What that means is analytical body-burden data collection should be a medical norm, for a variety of substances: polychlorinated biphenyls, triazine herbicides (atrazin…

Is this even worth doing when people are still smoking, drinking alcohol, living in polluted areas and eating red meat? These are all known risk factors with large effects on cancer risk in younger people.

I think the effort is better spent as follows:

- ban sale of combustible tobacco products

- ban advertising of alcoholic beverages

Re: Is early-onset cancer an emerging global epidemic?

#158

Post by SigmundA »

letsgo39 wrote: post #5
phkahler wrote: post #3

>> Increased use of screening programmes has contributed to this phenomenon to a certain extent, although a genuine increase in the incidence of early-onset forms of several cancer types also seems to have emerged. How do they separate these two. Early testing is becoming more common so you expect to see more cancer simply due to looking for it. Doc: Early screening has increased the 5-year survival rate for various…

You should be able to see the 'real' increase from death rates, assuming the cause of death is correctly identified as cancer pre or post mortem.

Cancer death rates are going down [1], which to me means we are probably better at treating cancer but also probably finding it more often even when not life threatening and might have gone on unnoticed in an earlier time.

Also we are getting better at treating other diseases and living longer, leading to being more likely to get cancer since if you live long enough you will almost certainly get some form of it.

1. https://www.cdc.gov/cancer/dcpc/research/update-on-cancer-de...

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