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Is early-onset cancer an emerging global epidemic?

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Re: Is early-onset cancer an emerging global epidemic?

#61

Post by lambdaba »

Test0129 wrote: post #46
lambdaba wrote: post #20

Earlier quoted context omitted.

Just adding a bit about the subject at hand: I am convinced the cancer epidemic is due to us grossly misusing our biological equipment: we are meant to feast & fast, and not have insulin's anabolic effects constantly activated. Fasting is crucial for "system maintenance", via autophagy (self-eating of damaged cells). Average person constantly stimulates insulin with following the advice of eating small meals often, w…

I've done fasting for a while. It's not the panacea that it's touted as. I was a pretty religious (figuratively) 16 hour fast person. I have several years of bloodwork to show marginal if any changes to baseline. In some cases, for example with blood sugar, there's a small window where insulin actually spikes during a fast. I had several unusual blood sugar readings if I took them around the 15 hour mark along with o…

> I climb often (vigorously, 4 times a week if not more)

You're very active! Even so, I wouldn't think the IF itself was the problem, probably you were having trouble eating enough for your level of activity with such a regimen.

About bloodwork, I believe you're mistakingly conflating insulin and blood sugar. Blood sugar may vary in such a way, but it's just a proxy because insulin is so hard to measure.

But more to the point, I wasn't referring to intermittent fasting solely, I believe even longer fasting periods are required. Regardless, even IF is a far cry from what the average person does.

I also disagree that fasting is not a panacea. It's a close to one as we have. I don't think this is a subject I'm likely to convince skeptics in a comment, so I will simply say interested people will find reputable resources on the subject, including striking anecdotes published by fasting clinics (of which, for some reason, Germany has a few that publish material on YouTube).

Re: Is early-onset cancer an emerging global epidemic?

#62

Post by lambdaba »

candiddevmike wrote: post #34
lambdaba wrote: post #20

Earlier quoted context omitted.

Just adding a bit about the subject at hand: I am convinced the cancer epidemic is due to us grossly misusing our biological equipment: we are meant to feast & fast, and not have insulin's anabolic effects constantly activated. Fasting is crucial for "system maintenance", via autophagy (self-eating of damaged cells). Average person constantly stimulates insulin with following the advice of eating small meals often, w…

Autophagy keeps getting brought up with such pseudoscientific bullshit explanations that I can't help but see it as snake oil. Furthermore, depending on who is describing it, the window for autophagy to kick in is anywhere from 8-48+ hours.

I don't know what science you need to understand a system that is constantly active and is never fully allowed to rest will develop dysfunction. Anyway, as the sibling reply says, there is plenty of reputable research available to satisfy your curiosity if you wish.

Re: Is early-onset cancer an emerging global epidemic?

#63

Post by lambdaba »

andrepd wrote: post #48
lambdaba wrote: post #15

Earlier quoted context omitted.

The result of misguidance from health professionals, big food & big pharma marketing. Not acknowledging that health is largely a result of lifestyle choices, and that pharmaceuticals are mostly ineffective and often harmful. And now for the specifics: - lies/bad science about meat (particularly red meat) being unhealthy - lies/bad science about cholesterol & saturated fat being unhealthy - not attacking sugar and pro…

> lies/bad science about cholesterol & saturated fat being unhealthy Are you saying cholesterol and saturated fats aren't unhealthy? I'm confused.

Yes, check out this report from Credit Suisse that sums up the state of the art research on the topic: https://research-doc.credit-suisse.com/docView?language=ENG&...

Bottom line is saturated fat is not implicated whatsoever in any negative health outcomes.

Re: Is early-onset cancer an emerging global epidemic?

#64

Post by pastor_bob »

notamy wrote: post #9

The most disturbing part, to me, is this: > The early-onset cancer epidemic might be one manifestation of increasing trends in the development of many chronic diseases in young and future generations. Why are chronic diseases trending upwards? Is it the obvious things (pollution, microplastics, obesity, massive drain on mental health from the modern lifestyle, etc.), or is there something else going on?

A lot of these chronic diseases are autoimmune ones.

I now know plenty of young people IBD, MS, Psoriasis, and even Rheumatoid Arthritis.

These seem to be caused by less obvious things imo (MS although looks linked to epstein-barr), as otherwise general health doesn't seem to be poor.

Re: Is early-onset cancer an emerging global epidemic?

#65

Post by lambdaba »

vibrio wrote: post #32
lambdaba wrote: post #15

Earlier quoted context omitted.

The result of misguidance from health professionals, big food & big pharma marketing. Not acknowledging that health is largely a result of lifestyle choices, and that pharmaceuticals are mostly ineffective and often harmful. And now for the specifics: - lies/bad science about meat (particularly red meat) being unhealthy - lies/bad science about cholesterol & saturated fat being unhealthy - not attacking sugar and pro…

I agree sugar is bad, cancer reseracher Lew Cantley has written very clearly scientifically about how High-fructose corn syrup is very bad supported with a lot of mechanistic data. I also agree health is largely a result of lifestyle choices for most-- it is what we can control. I can't even begin to contemplating support of many of your other statements. i wish you health and peace of mind.

There might be some unique harms from HFCS but I doubt they're anything but minor over harm from all fructose in refined form (so incl. and perhaps especially fruit juices and other junk often fed to children).

Re: the cholesterol, check out my other comment.

Thank you, wishing you the same.

Re: Is early-onset cancer an emerging global epidemic?

#66

Post by Jill_the_Pill »

MonkeyMalarky wrote: post #29

If we're going to throw out random theories for the cause like diet and pollution, what about all the volatile chemicals off-gassing from freshly manufactured goods?

I also wonder about exposure in youth to nuclear weapons testing fallout. That might show an identifiable spatial or temporal pattern, maybe falling off in more recent years and clustered among downwinders worldwide.

Re: Is early-onset cancer an emerging global epidemic?

#68

Post by lm28469 »

daniel-cussen wrote: post #4

Free radicals in the water table. Pollution in general. Plastic in the rainwater. Doesn't just affect nature. Backs up up the water table, from ocean to river from the slums to the hills. Good that we're doing it less and less, in some respects. Pollution is poison. Although there is always some. Even very primitive societies eg in the Amazon Basin pollute a bit and after like ten years they move to a new place, and…

> Doesn't just affect nature

Well it does, we're not outside of nature

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