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Is early-onset cancer an emerging global epidemic?

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51–60 of 280 posts

Re: Is early-onset cancer an emerging global epidemic?

#51

Free radicals in the water table. Pollution in general. Plastic in the rainwater. Doesn't just affect nature. Backs up up the water table, from ocean to river from the slums to the hills. Good that we're doing it less and less, in some respects. Pollution is poison. Although there is always some. Even very primitive societies eg in the Amazon Basin pollute a bit and after like ten years they move to a new place, and…

No post body was provided.

Re: Is early-onset cancer an emerging global epidemic?

#52
post #36

Earlier quoted context omitted.

> following the advice of eating small meals often This must be an american thing. I've always been told the opposite advice all my life. Interesting.

Eating small meals often is a way people control urge and hunger. I don't think it's American only. For a LONG time bodybuilding touted the 6 meals a day to lose weight strategy.

I get that people do it, it's just that I've never gotten the advice to do it (non body building contexts, just normal life). To "småäta" in sweden is a widely talked about thing to avoid (i.e. adviced against).

Re: Is early-onset cancer an emerging global epidemic?

#53

Earlier quoted context omitted.

> bad science... > I say this for experience... > It checks out for me... Glad you've managed to avoid the pesky allure of bad science with your anecdotal approach!

Are you trying to make the counter point that sugar and highly processed foods are healthy? There's lots of good science and history (! I guess that's just a bunch of anecdotes though) which demonstrates their ill effects. Sometimes, a fact has been asserted widely enough that we stop requiring sources, even at HN

More that he's critical of the thought process you've applied. You're conclusions are correct, so no one should be critical of that :)

Re: Is early-onset cancer an emerging global epidemic?

#55

If we're going to throw out random theories for the cause like diet and pollution, what about all the volatile chemicals off-gassing from freshly manufactured goods?

This is known issue, at least of late. There was a recent article posted here (can’t find it right now on mobile) about how that New Car Smell is caused, to some degree, by known carcinogens.

Re: Is early-onset cancer an emerging global epidemic?

#57

Earlier quoted context omitted.

Just adding a bit about the subject at hand: I am convinced the cancer epidemic is due to us grossly misusing our biological equipment: we are meant to feast & fast, and not have insulin's anabolic effects constantly activated. Fasting is crucial for "system maintenance", via autophagy (self-eating of damaged cells). Average person constantly stimulates insulin with following the advice of eating small meals often, w…

Autophagy keeps getting brought up with such pseudoscientific bullshit explanations that I can't help but see it as snake oil. Furthermore, depending on who is describing it, the window for autophagy to kick in is anywhere from 8-48+ hours.

There is a lot of "bro-science" out there concerning autophagy for sure, but it is definitely a thing. Yoshinori Ohsumi won the Nobel Prize in Physiology or Medicine in 2016 for "his discoveries of mechanisms for autophagy" (https://www.nobelprize.org/prizes/medicine/2016/summary/).

Re: Is early-onset cancer an emerging global epidemic?

#58

Earlier quoted context omitted.

Just adding a bit about the subject at hand: I am convinced the cancer epidemic is due to us grossly misusing our biological equipment: we are meant to feast & fast, and not have insulin's anabolic effects constantly activated. Fasting is crucial for "system maintenance", via autophagy (self-eating of damaged cells). Average person constantly stimulates insulin with following the advice of eating small meals often, w…

I've done fasting for a while. It's not the panacea that it's touted as. I was a pretty religious (figuratively) 16 hour fast person. I have several years of bloodwork to show marginal if any changes to baseline. In some cases, for example with blood sugar, there's a small window where insulin actually spikes during a fast. I had several unusual blood sugar readings if I took them around the 15 hour mark along with o…

I don't really agree with the parent's assessment that lack of fasting-induced autophagy is the reason for the increase in cancer, but your anecdote about 16 hour fasts is sorta irrelevant.

Autophagy doesn't really kick in until 2-3 days of fasting.

Re: Is early-onset cancer an emerging global epidemic?

#59
post #48

Earlier quoted context omitted.

The result of misguidance from health professionals, big food & big pharma marketing. Not acknowledging that health is largely a result of lifestyle choices, and that pharmaceuticals are mostly ineffective and often harmful. And now for the specifics: - lies/bad science about meat (particularly red meat) being unhealthy - lies/bad science about cholesterol & saturated fat being unhealthy - not attacking sugar and pro…

> lies/bad science about cholesterol & saturated fat being unhealthy Are you saying cholesterol and saturated fats aren't unhealthy? I'm confused.

It turned out eating high cholesterol foods didn’t lead to high cholesterol after all.

Re: Is early-onset cancer an emerging global epidemic?

#60
post #9

The most disturbing part, to me, is this: > The early-onset cancer epidemic might be one manifestation of increasing trends in the development of many chronic diseases in young and future generations. Why are chronic diseases trending upwards? Is it the obvious things (pollution, microplastics, obesity, massive drain on mental health from the modern lifestyle, etc.), or is there something else going on?

The result of misguidance from health professionals, big food & big pharma marketing. Not acknowledging that health is largely a result of lifestyle choices, and that pharmaceuticals are mostly ineffective and often harmful. And now for the specifics: - lies/bad science about meat (particularly red meat) being unhealthy - lies/bad science about cholesterol & saturated fat being unhealthy - not attacking sugar and pro…

> I'd also add that these things compound over the generations. We are more sensitive than our parents. It checks out for me, every generation has worsening autoimmune symptoms.

This may just be a function of increasing pollen overstimulating the immune system. In the last 30 years pollen counts have gone up 20+%[1]. Turns out trees like carbon and warmer air.

Anecdotally both of my kids have seasonal allergies, neither me nor my wife did when we were kids.

https://www.hsph.harvard.edu/news/hsph-in-the-news/pollen-se...

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