Earlier quoted context omitted.
Programming machines to make the trip and then seeding with human life seems to be the best answer to distance.
That would be so interesting - could be many a sci-fi stories created on that premise. Some mechanical robot/starship storing frozen embryos for 100 years to be released on a far-away exoplanet, the starship taking care of them while they grow up and learn how to live on this new world - the beginnings of a new civilization - a technological adam and eve of sorts.
Here is a very short synopsis on the authors website in English: https://steinmuller.de/en/sf-literatur/science-fiction-buech...