Earlier quoted context omitted.
And what conditions did you cure with this regime? Did your overall calorie intake remain the same?
Benign tumors on my skin disappeared and I lost 80 pounds
Benign tumors? Moles?
Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
51–60 of 228 posts
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#52Maybe I missed this, but 2 weeks in fruit flies and 3 months in mice probably translates into something much longer in humans, on the order of a year or two maybe, if not longer? That's a pretty long time to be on an immune-suppressing drug with pretty significant side effects.
It's still an important bit of information if it replicates, but I think it might not be as clinically practical as it sounds from the press release.
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#53What's the latest on bloodboys? That is : periodic blood transfusion from healthy young vegan donor. It works very well. Rejuvenates ancient billionaires. Surely it's superpopular among the oligarchs. Probably not the kind of thing you want in the news (vampires!). The technical term is Parabiosis . These guys offer the service : https://www.ambrosiaplasma.com/
Gavin Belson approved.
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#54genuine question: why would someone want to live longer than the average? Edit: I ask because I personally don't see a reason to stay alive while people I love are dying, I don't see a reason to stay alive in an already fucked up planet, while we empty all the resources, etc. But you guys are so smart, intelligent and clever, why even bother.
Average life expectancy in the US is 78, with some states seeing average age around 74.
Do you want to live no longer than average, so lets call it no older than 75?
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#55The bigger story with rapamycin is that the mechanistic target of rapamycin (mTOR) plays an absolutely crucial role in major diseases of modern civilization. One of the ways to inhibit mTOR for free is to simply stop consuming nutrients for extended periods of time.
As added information: metformin, a common anti-diabetic drug, is a inhibitor of mTOR. It potential adverse effects are less severe than rapamycin but are still significant. Specifically, long term usage can cause renal damage. Its mechanism of action has yet to be fully elucidated.
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#56Anyone taking or have taken Rapamycin or things that change mTor? How did that go? Is there risk of infections?
David Sinclair got me interested in this topic.
Also people who fast for a long time: How do you do that? I get super hangry and find it really a struggle past a certain point of not eating.
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#57I have been taking rapamycin for many years now. It's obviously not ready for anywhere near the general public and is never something I'd suggest to someone at this point, but my own results have been wonderful and my blood panels and energy levels are great. If I had to guess, when properly used, this would probably add a full 5-10 years onto the lifespan of a lot of people. When combined with many other promising treatments, I think we could easily add 10-15 years onto most peoples' health+lifespans.
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#58Hopefully they mean aging remedy not anti-aging remedy...
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#59Earlier quoted context omitted.
It's generally not maximizing lifespan people are interested in but rather maximizing health span which is the period of time you are healthy and able to operate at a high level. If done correctly you die with minimum time spent disabled.
If you max health span, you're going to live longer. If you die, you're probably not healthy to begin with, or you die to very sudden trauma.
any brain disease that makes you mentally unhealthy but lets your body survive comes to mind
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#60How does one find a doctor willing to prescribe these kinds of drugs for anti aging?
I'm not taking Rapamycin due to costs and immune system concerns, but when researching this niche (specifically, I'm interested in senolytics) I have found this forum with this list of doctors https://age-reversal.net/physician-directory/ Maybe it could help you.
Very helpful. Thank you