Earlier quoted context omitted.
I've worked on mice before and frankly I have no clue what sort of technical requirement would lead to an upside down charging requirement and disabling the functionality in the meantime. Can you explain what that reason might be? Also if most people can't just pick up the mouse and use it, it's a broken design. In my particular case, it's so much smaller than my palm that I'm sure any grip would result in RSI.
Simple, the front is not thick enough to accommodate a common port like USB or Lightning. If you put it on the sides, it defies the purpose. Changing the design to accommodate a port in the front doesn't make sense because the primary function of the device is to act as a human-computer interface and optimising the design for that purpose is paramount, charging is not a primary function but something that we have to…
Then fire Jony Ive and make the front thicker! This isn't exactly rocket surgery.