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Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

nature.com

91–100 of 303 posts

Re: Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

#91

Been doing it for some months on & off, this shit is legit. Altough 0,5g has me tripping so I rarely dose above 100 milligrams. Get up early, do a workout, take cold shower, meditate and then pop a microdose shrooms, feels great. Microdosing is like steroids for meditation. Especially helpful for the programmer logic types of people like me, gets you out of your head for some time and helps you connect with your emot…

> Been doing it for some months on & off, this shit is legit

The linked study seems to contradict you:

>> According to our findings, low doses of psilocybin mushrooms can result in noticeable subjective effects and altered EEG rhythms, but without evidence to support enhanced well-being, creativity and cognitive function. We conclude that expectation underlies at least some of the anecdotal benefits attributed to microdosing with psilocybin mushrooms.

Re: Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

#92

Earlier quoted context omitted.

Does "if it works for you" also go for things like aspirin, antihistamines, antihypertensives, antibiotics, etc? I've never heard anyone say "if aspirin works for you then take it, but it doesn't work for me". I've only heard this kind of thing said for things like homeopathy, astrology, accupuncture, osteopathy, and microdosing, of course. Hence, I'm very skeptical. [Edit: OK, I've heard people say that aspirin does…

psychoactive drugs are a whole different category. You bring your whole mental baggage with you when you take them, unlike aspirin.

How do you define "psychoactive"?

Re: Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

#93

I have been interested for quite some time to dabble with psilocybin but just haven't yet had the chance with buddies(outside of a work related traveling event) to do so. I absolutely refuse to try anything like this outside of an environment I have some level of control in or trust in the people around me(not the general public I.E: Bars, clubs, Vegas, etc). Any advice on what to avoid for a first timer from any exp…

I would say that if you want to maintain your cognitive function at peak efficiency your best bet is to not do anything that has a chance to affect it negatively, like doing drugs.

An "experienced person" in this case will not help you because it means someone who's been doing drugs for a while and there is at least a chance that their cognitive function is impaired and that you shouldn't trust their judgement.

Re: Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

#95

Earlier quoted context omitted.

Have you tried Kratom? I'm by no means recommending it, just curious if you've tried it to combat depression.

As a daily Kratom user, I would not recommend using Kratom for something like depression. You're treating the symptomps at best while cultivating addiction.

Yeah, always best to not fuck around with chemicals that bind to gabba receptors (alcohol, benzodiazepine, kratom). It will give you a hell of a withdrawal if you take high doses. This is why there are alcoholics.

Re: Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

#96

Earlier quoted context omitted.

Yeah, drugs feel great, news at 11. If psychiatry was just a matter of giving people a constant buzz, it would be solved a century ago. I'm not judging you for wanting to be high all the time, I've been there myself. But be intellectually honest and call it that, at least. Because it's not some kind of psychological panacea, and I wish people would stop implying it is. And yes, I've tried it. It made me high, but gen…

Uh, so you took a break from your ADHD medication to microdose? And you claim it is the microdose that made you less productive? I posit you need to take a microdose with your normal ADHD medication, otherwise the anecdote is meaningless even as a personal reference.

No post body was provided.

Re: Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

#97
post #3

(It's strange that we're using the term microdose, even in scientific contexts - prefixes have meanings - it should be called a decidose.) Anecdotally, I've had a degree of short term success treating my depression with smallish doses of mushrooms, but I've never had the continuing access required for a microdosing regiment. It'd be nice if the government were willing to come to the table on this, but alas. That said…

I think decidose would be even less accurate. A normal dose is 3g-5g. A microdose is 0.1g-0.2g. That's not a ratio of 10. At least microdose has a widely-agreed on colloquial meaning.

Re: Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

#98
post #85

Earlier quoted context omitted.

It can be a "party drug" if you dose low, especially if you are chilling at a bar with friends. Just pushes you into a slightly better mood. I'll rather have a microdose with some beers than getting shitfaced drunk, feels subjectively healthier to me.

Of course you could also just stop drinking after a few beers without taking additional drugs.

easier said than done. But you are right of course, that's where you want to go.

Re: Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

#99

Earlier quoted context omitted.

Does "if it works for you" also go for things like aspirin, antihistamines, antihypertensives, antibiotics, etc? I've never heard anyone say "if aspirin works for you then take it, but it doesn't work for me". I've only heard this kind of thing said for things like homeopathy, astrology, accupuncture, osteopathy, and microdosing, of course. Hence, I'm very skeptical. [Edit: OK, I've heard people say that aspirin does…

psychoactive drugs are a whole different category. You bring your whole mental baggage with you when you take them, unlike aspirin.

[deleted]

Re: Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

#100

Earlier quoted context omitted.

psychoactive drugs are a whole different category. You bring your whole mental baggage with you when you take them, unlike aspirin.

How do you define "psychoactive"?

Anything that influences your psyche in an obvious way.
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