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Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

pubmed.ncbi.nlm.nih.gov

61–70 of 166 posts

Re: Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

#61
post #39

Apparently everyone is downvoting everything they can because this is a sensitive topic. I'd just like to call out, where feminization is a major concern (US, maybe Europe), there is less than 1ng/L of this compound in water, see elsewhere on this thread for the graphic. The lowest dose of EE2 for trans-women is 2mg a day orally. That means whatever the dosage is in the US it's less than 1/10th* of what trans folk fi…

Trans women typically take E2 (bioidentical estrogen), not EE2. EE2 is 100 times more potent than E2 for certain endocrine interactions. Unlike E2, EE2 is not a naturally occurring hormone. E2 causes female puberty when administered to males (except for menstruation), but EE2 isn’t necessarily going to do the same thing because it is a different molecule. While worrying about “feminizing” is probably hype, worrying a…

Thank you for the correction!

Re: Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

#62

Earlier quoted context omitted.

I agree! I explicitly state that I don't think random pollutants are good in that comment and there could be other reasons to care about it. I'm merely calling out that the thing most people freak out about with this compound (feminization) is not worth freaking out about .

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Re: Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

#63
post #52
post #30

Earlier quoted context omitted.

Not really. EE2 is used in birth control but the spike in people being transgender (or being openly transgender, at least) does not line up with the adoption of EE2 BC (which started in the 1960s - if that was the case you’d expect to see a bunch of transgender people who grew up around then, so ages 50-70). Further, spikes in EE2 cannot explain the prevalence of female-to-male transgender people.

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Possibly - although it still doesn’t explain FTMs. “Society got more accepting” seems like a much simpler theory that explains the rise in trans people. Doesn’t mean environmental estrogen isn’t a health risk, though.

Re: Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

#64
post #40

Apparently everyone is downvoting everything they can because this is a sensitive topic. I'd just like to call out, where feminization is a major concern (US, maybe Europe), there is less than 1ng/L of this compound in water, see elsewhere on this thread for the graphic. The lowest dose of EE2 for trans-women is 2mg a day orally. That means whatever the dosage is in the US it's less than 1/10th* of what trans folk fi…

> I'd just like to call out, where feminization is a major concern (US, maybe Europe) What’s that supposed to mean? The article shows the rates in Southeast Asia are 10 times higher than the US. I can assure you that “feminization” would be a much more significant concern there than in the US or Europe.

i think OP's two points are that

1. backlash against "feminization of men" is something that people seem to care about more in the USA than other countries (HN audiences skew toward this population anyway);

2. these days, right-wing extremists in my country (USA) see "feminization of men" as a politically beneficial wedge issue, and this politicization makes it impossible to study the actual societal effects impartially/neutrally.

Re: Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

#66
post #52
post #30

Earlier quoted context omitted.

Not really. EE2 is used in birth control but the spike in people being transgender (or being openly transgender, at least) does not line up with the adoption of EE2 BC (which started in the 1960s - if that was the case you’d expect to see a bunch of transgender people who grew up around then, so ages 50-70). Further, spikes in EE2 cannot explain the prevalence of female-to-male transgender people.

Quoted post unavailable.

It's not taboo.

Re: Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

#67

Apparently everyone is downvoting everything they can because this is a sensitive topic. I'd just like to call out, where feminization is a major concern (US, maybe Europe), there is less than 1ng/L of this compound in water, see elsewhere on this thread for the graphic. The lowest dose of EE2 for trans-women is 2mg a day orally. That means whatever the dosage is in the US it's less than 1/10th* of what trans folk fi…

[deleted]

Re: Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

#68

> Another potential contamination of EE2 is aquaculture. Based on a recent investigation, high concentrations of EE2 ranging from Why is aquaculture waste water contributing to EE2 contamination? What step in aquaculture would create this..

Female fish are generally bigger than male fish and caviar can only be harvested from females.

The example source in the paper is in Malaysia which I think is a bit too warm for sturgeon.

Re: Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

#70
post #8

I'm concerned this is making numbers here because of fear mongers so I want to run the numbers a bit to > The top 10 countries ranked in the order of high to low average EE2 concentration in surface water, were Vietnam, Cambodia, China, Laos, Brazil, Argentina, Kuwait, Thailand, Indonesia and Portugal, with the respective mean concentrations of 27.7, 22.1, 21.5, 21.1, 13.6, 9.6, 9.5, 8.8, 7.6 and 6.6 ng/L Going by Wi…

Ideology doesn't factor into this. There is something in the water that shouldn't be there, and someone put it there---largely without permission. And what constitutes a "low dose" frequently changes by several orders of magnitude depending on who does the study, and who paid for the study.

Ideology doesn’t factor into this?

Seems odd to say in an era where hormone therapy is being normalized and science is weaponized for ideological purposes regularly.

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