Review of 17α-ethynylestradiol in water across 32 countries: Estrogenic effects

Post by sudosysgen » Sat, Jul 30, 2022, 3:08 PM UTC

elil17 wrote: post #39

marricks wrote: post #23

Apparently everyone is downvoting everything they can because this is a sensitive topic. I'd just like to call out, where feminization is a major concern (US, maybe Europe), there is less than 1ng/L of this compound in water, see elsewhere on this thread for the graphic. The lowest dose of EE2 for trans-women is 2mg a day orally. That means whatever the dosage is in the US it's less than 1/10th* of what trans folk fi…

Trans women typically take E2 (bioidentical estrogen), not EE2. EE2 is 100 times more potent than E2 for certain endocrine interactions. Unlike E2, EE2 is not a naturally occurring hormone. E2 causes female puberty when administered to males (except for menstruation), but EE2 isn’t necessarily going to do the same thing because it is a different molecule. While worrying about “feminizing” is probably hype, worrying a…

Post by baldisbasics » Sat, Jul 30, 2022, 3:11 PM UTC

sudosysgen wrote: post #47

baldisbasics wrote: post #38

I swear, everyone in my part of the US had massive hair shedding around 2018 or so (man and woman, young and old). We speculated at the time that maybe something in the water supply was causing everyone to lose hair in clumps, and by golly this appears to match with our pet theories.

Estrogen doesn't cause hair loss in general.

Post by [deleted] » Sat, Jul 30, 2022, 3:12 PM UTC

rayiner wrote: post #40

marricks wrote: post #23

Apparently everyone is downvoting everything they can because this is a sensitive topic. I'd just like to call out, where feminization is a major concern (US, maybe Europe), there is less than 1ng/L of this compound in water, see elsewhere on this thread for the graphic. The lowest dose of EE2 for trans-women is 2mg a day orally. That means whatever the dosage is in the US it's less than 1/10th* of what trans folk fi…

> I'd just like to call out, where feminization is a major concern (US, maybe Europe) What’s that supposed to mean? The article shows the rates in Southeast Asia are 10 times higher than the US. I can assure you that “feminization” would be a much more significant concern there than in the US or Europe.

Post by elil17 » Sat, Jul 30, 2022, 3:14 PM UTC

gcr wrote: post #46

elil17 wrote: post #39

Earlier quoted context omitted.

Trans women typically take E2 (bioidentical estrogen), not EE2. EE2 is 100 times more potent than E2 for certain endocrine interactions. Unlike E2, EE2 is not a naturally occurring hormone. E2 causes female puberty when administered to males (except for menstruation), but EE2 isn’t necessarily going to do the same thing because it is a different molecule. While worrying about “feminizing” is probably hype, worrying a…

Back in the day ('70s and '80s i think), trans women used to take synthetic estrogens (such as premarin, IIRC was the drug of choice) before switching to bioidentical estrogen from estradiol tablets in the '90s and '00s, I think because bioidentical E is seen as more effective with a softer side effect profile than the synthetics, in particular bioidentical doesn't hurt the liver as much. Drinking horse piss in the 7…

Post by davmar » Sat, Jul 30, 2022, 3:15 PM UTC

marricks wrote: post #8

I'm concerned this is making numbers here because of fear mongers so I want to run the numbers a bit to > The top 10 countries ranked in the order of high to low average EE2 concentration in surface water, were Vietnam, Cambodia, China, Laos, Brazil, Argentina, Kuwait, Thailand, Indonesia and Portugal, with the respective mean concentrations of 27.7, 22.1, 21.5, 21.1, 13.6, 9.6, 9.5, 8.8, 7.6 and 6.6 ng/L Going by Wi…