Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

People with low BMI aren't more active, they are just less hungry, 'run hotter'

sciencedaily.com

Post reply on HN
Print view View original

301–310 of 350 posts

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#301

Post by csours »

frotak wrote: post #251
csours wrote: post #77

Hunger is mediated by a bunch of hormones and you can test for some of those, but there is no test for the feeling of hunger. As a comparison, it is famously very hard for doctors to understand pain; it is also difficult for patients to communicate about pain. The feeling of hunger is not comparable between people. Hunger is driven by multiple sensations (blood sugar, stomach stretch, hormone levels) and by cognitive…

> losing body fat means that you must continuously make choices that decrease your comfort in some way - eating fewer highly rewarding foods, maintaining a state of hunger, increasing activity level It is interesting to see "increasing activity level" as being a decrease in comfort. But I suppose that's because "comfort" here isn't defined absolutely. I also am not sure that "comfort" is an attribute that should be o…

I don't like to sweat. I did construction work with my dad in the Texas heat. When I looked at careers, I chose one that I can do indoors.

I'm not saying that is good, I'm saying that is a strong value statement that I made when I was younger. It's hard to change values, even in the face of evidence.

I think people should find exercise that they enjoy. I have struggled with this due to other physical limitations (in addition to my weight) and my attitude and cognitive behaviors. I now enjoy riding my bike, hiking, and swimming.

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#302

Post by csours »

convexfunction wrote: post #156
csours wrote: post #77

Hunger is mediated by a bunch of hormones and you can test for some of those, but there is no test for the feeling of hunger. As a comparison, it is famously very hard for doctors to understand pain; it is also difficult for patients to communicate about pain. The feeling of hunger is not comparable between people. Hunger is driven by multiple sensations (blood sugar, stomach stretch, hormone levels) and by cognitive…

> losing body fat means that you must continuously make choices that decrease your comfort in some way - eating fewer highly rewarding foods, maintaining a state of hunger, increasing activity level Not necessarily! I've successfully lost a lot of body fat (~50 pounds over the last 18 months) by deliberately changing my diet to eat more foods (that I like) that are lower in energy density than what I was eating befor…

I'm happy for you! But this is exactly what I mean about the feeling and experience of hunger not being comparable.

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#303

Post by FollowingTheDao »

dilap wrote: post #155
wowokay wrote: post #100

Earlier quoted context omitted.

That’s very interesting. I’m curious how it could relate to humans. Not to say it can’t be 1:1, but there are mental aspects that can effect human hunger and I’d be interested in research around that. For example someone who eats a lot but falls into a depression might slow eating considerably (or eat more depending on the person) it’s not to far fetched to consider the possibility of mind state altering medication t…

Absolutely, the mental aspects of hunger are huge, as anyone who has ever had the munchies (super hungry) or taken adderall (super not hungry) can attest. In fact, n6 fats may also promote hunger, via increasing endocannabinoid production. Here's a study I just found in mice: https://pubmed.ncbi.nlm.nih.gov/24081493/ Again just an animal model, but certainly suggestive...

Omega 3 also increases endocannabinoids, but a different form:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685292/

AEA and 2-AG are synthesized from omega-6 polyunsaturated fatty acid (PUFA), arachidonic acid (AA), and are hydrolyzed by fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL),

Herein, we review the discovery and physiological role of omega-3 eCBs that are derived from DHA and EPA (Figure 1A). We illustrate that the derivatization of carboxylic acid end of the omega-3 fatty acid with ethanolamide, glycerol or other groups, such as neurotransmitters, leads to substantial changes in their biological activity and receptor interactions. We also review the discovery, mechanism and activity of the following omega-3 eCBs- DHA-ethanolamide (DHA-EA), 2-docosahexaenoyl-glycerol (2-DHG) and eCB-like- DHA-serotonin (DHA-5HT), DHA-dopamine (DHA-DA) and the EPA analogs.

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#304

Post by FollowingTheDao »

tmjdev wrote: post #179
dilap wrote: post #78

There's a really interesting study they did with pigs. They fed pigs four different diets that had the same amount of calories, but varying ratios of n3/n6 fats. The pigs with high n6/n3 ratio ended up much fatter and less muscular than the pigs eating a 1-1 ratio diet. It's a very neat demonstration that "all that matters is calories" is not true; your metabolism, and thus how you use the calories, is influenced by…

If it was the ratio being studied, could you instead increase your n3 fat consumption?

I do not think so in my opinion, since Omega 3 and Omega 6 compete for the same enzymes.

https://pubmed.ncbi.nlm.nih.gov/25373089/

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#305

Post by matthewdgreen »

nradov wrote: post #288
matthewdgreen wrote: post #283

Earlier quoted context omitted.

Having seen friends and relatives succumb to cardiovascular disease, it's really heartbreaking. I've watched people starve themselves on brown rice and broccoli for years (with only modest results, followed by total failure) because diet-only interventions are completely unrealistic and don't work long term.

Those friends and relatives weren't really starving themselves brown rice and broccoli. They were eating a bunch of other stuff when you weren't looking. We have existence proofs that diet-only interventions work for some people. I literally know people who have lost large amounts of weight and kept it off for years that way. Medications have risks and side effects, so should only be prescribed if behavior modificati…

We have many unsuccessful treatments that work for a small percentage of patients. That's why we measure treatments by effectiveness rather than identifying existence proofs that it worked for someone.

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#306

Post by dilap »

KapKap55 wrote: post #293
dilap wrote: post #78

There's a really interesting study they did with pigs. They fed pigs four different diets that had the same amount of calories, but varying ratios of n3/n6 fats. The pigs with high n6/n3 ratio ended up much fatter and less muscular than the pigs eating a 1-1 ratio diet. It's a very neat demonstration that "all that matters is calories" is not true; your metabolism, and thus how you use the calories, is influenced by…

Where in this study does it suggest that calorie intake was limited? The only line I saw relating to calorie management was this one: |All the pigs had ad libitum access to diets and water and consumed the diets for 2 months. So they could eat as much as they wanted to, it seems.

You are right, my mistake! I was mixing it up with another study. Unfortunately, it is too late to edit my comment.

However, coincidentally, the same conclusions still hold, since it turns out the pigs ate very similar amounts of food on all the diets, except the 5:1 n6:n3 diet, where they ate a bit less. (And that was the diet where the pigs gained the most weight.)

Sorry about the error!

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#307

Post by convexfunction »

tharkun__ wrote: post #238
SketchySeaBeast wrote: post #193

Earlier quoted context omitted.

They are trying to convince everyone that the fruit & veg & lean meats is every bit as enjoyable as a steak and piece of cheesecake. It may be for them, but as a rule I have my doubts.

They do it that way. It does not have to be. You just gotta eat different highly rewarding foods. E.g. do eat that steak. But without a BBQ sauce you bought. Just salt and pepper is great actually. But a butter and cream garlic sauce (no sugar) is also awesome. Maybe some blue cheese on top instead? Skip the potato. Just that steak with some nice caramelized onions or veggies you like as a side. But that's not even n…

And, well, I failed horribly at conveying my actual strategy (I guess we're getting hung up on "fruits, vegetables, and lean meats are supposedly not very rewarding"?) because I would describe what I'm doing as "eat different highly rewarding foods".

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#308

Post by nradov »

matthewdgreen wrote: post #305
nradov wrote: post #288

Earlier quoted context omitted.

Those friends and relatives weren't really starving themselves brown rice and broccoli. They were eating a bunch of other stuff when you weren't looking. We have existence proofs that diet-only interventions work for some people. I literally know people who have lost large amounts of weight and kept it off for years that way. Medications have risks and side effects, so should only be prescribed if behavior modificati…

We have many unsuccessful treatments that work for a small percentage of patients. That's why we measure treatments by effectiveness rather than identifying existence proofs that it worked for someone.

You're really missing the point. Every patient is unique. That's why competent healthcare providers take a step therapy approach and try cheaper, lower-risk treatments first before moving on to more expensive and riskier medication or bariatric surgery.

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#309

Post by SketchySeaBeast »

convexfunction wrote: post #279
SketchySeaBeast wrote: post #232

Earlier quoted context omitted.

I agree that a salmon filet is tasty. I don't often eat a pound of strawberries though. Both of those are too expensive to eat regularly, and like you said a salmon filet is a lot of effort compared to a burger. > I'll have the cheesecake if I really feel like it. That tells me the writing on the wall, and let me be clear about this, the writing is what needs to be written and what people need to read - you're making…

> That tells me the writing on the wall, and let me be clear about this, the writing is what needs to be written and what people need to read - you're making the decision to NOT have cheesecake when you only kind of feel like it. It's a game of weighing the pros and cons and learning to be satisfied with what you know you should have instead of turning around one day and loving the healthy food more than the unhealth…

Do you weigh everything you eat?

Re: People with low BMI aren't more active, they are just less hungry, 'run hotter'

#310

Post by jliptzin »

xhr_2 wrote: post #191
jliptzin wrote: post #145

Earlier quoted context omitted.

Same for me. Even as Ive tried to gain weight, my weight barely budged. 150-155 for at least the last 10 years. I have obese (300lb+) friends and they insist they don’t eat that much more than me. Except they do. We go out to eat, we stop eating after about 5-10 min. I’m full and done. They burp a couple times, then proceed to keep eating, smothering everything in Mayo and bbq sauce. Then they get insane desserts. An…

Check out /r/noburp. I couldn't burp for most of my life until I taught myself.

Interesting thx
Post reply on HN