Pepsi, Tropicana and the like, and their parent companies, are a direct cause of the Metabolic Syndrome epidemic in (particularly) the US, other former UK colonies, and UK, causing many times the preventable deaths from COVID, year in and year out. The "cause of death" noted for these cases never mentions metabolic syndrome (variously, fatty liver disease, cirrhosis, processed-food disease), but rather secondary illn…
There is plenty of diabetes and obesity in Australia and we don't use fructose as a sweetener. I'm not sure fructose is necessary.
Grapes, almost uniquely among fruits, have practically no fiber, so are as bad as juice.
The glucose part of sugar is mostly harmless. So we focus on the fructose.