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Pretty much every culture around the world 100 years ago had some staple fermented food. Nowadays, a lot of people in western culture at least outright refuse yogurt or other fermented foods like saurkraut or pickled cabbage that used to be staples in these people's ancestor's diets a few generations ago. People are becoming even lactose intolerant. You have to fertilize your microbes so to speak and eat these sorts…
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Pretty much every culture around the world 100 years ago had some staple fermented food. Nowadays, a lot of people in western culture at least outright refuse yogurt or other fermented foods like saurkraut or pickled cabbage that used to be staples in these people's ancestor's diets a few generations ago. People are becoming even lactose intolerant. You have to fertilize your microbes so to speak and eat these sorts…
Lactase (the enzyme that breaks down lactose) production is regulated by a human gene; how would a probiotic like yogurt alter a gene?
It's the iron fortified flour and then the people are like OMG I have celiac and what not. There's a reason breast milk and milk in general contains lactoferrin; guess what, they also remove it from most milk that is in supermarkets.
https://www.bsg.org.uk/covid-19-advice/covid-19-specific-non...
Earlier quoted context omitted.
How does one analyze the gut biome? I imagine it involves running poop through a machine - what kind of machine? I would love to learn more about the technical process.
The paper uses 16S rDNA sequencing, which is a bit old fashioned now but it was a good method when the paper was published. The steps basically involve: 1. Extract all DNA from poop, normally using a kit that basically makes DNA stick to tiny plastic beads. You wash the beads in a bunch of different chemical solutions to isolate DNA from the original sample and purify it. There are a lot of different methods to do th…
Pretty much every culture around the world 100 years ago had some staple fermented food. Nowadays, a lot of people in western culture at least outright refuse yogurt or other fermented foods like saurkraut or pickled cabbage that used to be staples in these people's ancestor's diets a few generations ago. People are becoming even lactose intolerant. You have to fertilize your microbes so to speak and eat these sorts…
Eating yogurt or sauerkraut will not render you (once again) lactose tolerant. Lactase (the enzyme that breaks down lactose) production is regulated by a human gene; how would a probiotic like yogurt alter a gene? https://biologydictionary.net/lactase/
That's what ruminents do anyways, you need a steady colony of these helpful bacteria or you lose the tolerance. While that seems troublesome, for many animals that's how metabolism works for their entire life.
>people in U.S. cities...people in less developed parts of the world What about people in the US who are not in cities? That's the more interesting comparison to me. Why would that be left out?
> What about people in the US who are not in cities? That's the more interesting comparison to me. Why would that be left out? At least in the US, my lay-intuition is that you wouldn't see much of a difference between average Americans between urban, suburban, and rural settings. That's perhaps worth testing, but I think the much more interesting test would be between wealth and class groups. (Again, wild speculation…
Can you elaborate on why you think this is the case? Intuitively to me, most folks’ diets are going to be mostly cooked eggs which would reduce any effect on bacteria in the gut.
Pretty much every culture around the world 100 years ago had some staple fermented food. Nowadays, a lot of people in western culture at least outright refuse yogurt or other fermented foods like saurkraut or pickled cabbage that used to be staples in these people's ancestor's diets a few generations ago. People are becoming even lactose intolerant. You have to fertilize your microbes so to speak and eat these sorts…
Eating yogurt or sauerkraut will not render you (once again) lactose tolerant. Lactase (the enzyme that breaks down lactose) production is regulated by a human gene; how would a probiotic like yogurt alter a gene? https://biologydictionary.net/lactase/
Just spitballing, this is pure speculation, but is plausible.
It's the diet. City dwellers tend to eat a lot more unhealthy foods. They also eat a lot less vegetables, fruit and nuts than their rural country(wo)men. You want more microbes in your gut? Eat more plant-based food.
It's the diet. City dwellers tend to eat a lot more unhealthy foods. They also eat a lot less vegetables, fruit and nuts than their rural country(wo)men. You want more microbes in your gut? Eat more plant-based food.
Having lived both in the city and fairly rural, I can say that access to a healthy and varied diet is much much easier in the city. Both when it came to restaurants and buying and cooking food.
That said bushland in Australia has natives that you can’t buy in the supermarket. So there is that.
But the average person probably doesn’t forage.