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Modern city dwellers have lost about half their gut microbes

science.org

11–20 of 318 posts

Re: Modern city dwellers have lost about half their gut microbes

#11
post #9

Earlier quoted context omitted.

I'm unable to verify that quote. Also, it's irrelevant, and not really true at all.

Quoted post unavailable.

You're right, I don't see the humour in this.

And it's not pedantic to question a misquoting when the meaning is completely different. Nor is it pedantic to question the relevance of someone's comment.

I don't think this quote means what you think it means.

Re: Modern city dwellers have lost about half their gut microbes

#13
post #5

>people in U.S. cities...people in less developed parts of the world What about people in the US who are not in cities? That's the more interesting comparison to me. Why would that be left out?

I'm curious why that comparison is more interesting to you? I can see great value in having both data points when trying to formulate a hypothesis about what causes the decline in gut-microbes in us city folks, but I find it hard to think of a use-case for solely a urban/rural comparison without other context.

(Update: I was thinking about this from a scientific perspective, ignoring the idea that people might be interested in what it means for them personally (facepalm) )

Re: Modern city dwellers have lost about half their gut microbes

#14
Once a gene has started expressing, it's pretty hard to flip the switch back to the off position. Losing the microbes is a big problem.

It's just going to get worse. People seem to have this fetish for anti-bacterial everything.. soaps, coatings, etc. They take anti-biotics even for viral issues then they wonder why they start developing a new health problem they didn't have before, like a mood disorder or an autoimmune issue.

Re: Modern city dwellers have lost about half their gut microbes

#15
My first thoughts are (without access to the actual article)

* We have lost the microbiome that primates present

* have we gained other microbes?

* what did those microbes we lost do? If they break down heavy fibre (branches) we may simply not need them, so evolution would stop selecting for them

* This says cities, but it (a) only appears to look at the US, and (b) the article doesn't mention comparing to non-city dwellers in the US. Saying "cities" without also providing a non-city reference seems bogus, but also could simply be left out of the article.

* Following from the "US only" comment above - how stable is this microbiome between geographical regions in the US?, how about different countries in close geographic location (think Europe)?, or geographically separated countries with similar culture? different culture?

All of these things might be answered in the paper, but per-usual Science has given us a fairly useless summary article with a clickbait headline :-(

[Edited to bring back formatting. For a text only, anti-emoji, etc site HN is obnoxiously opposed to basic white space formatting :-/]

Re: Modern city dwellers have lost about half their gut microbes

#16
post #13
post #5

>people in U.S. cities...people in less developed parts of the world What about people in the US who are not in cities? That's the more interesting comparison to me. Why would that be left out?

I'm curious why that comparison is more interesting to you? I can see great value in having both data points when trying to formulate a hypothesis about what causes the decline in gut-microbes in us city folks, but I find it hard to think of a use-case for solely a urban/rural comparison without other context. (Update: I was thinking about this from a scientific perspective, ignoring the idea that people might be int…

Because a bunch of us don't live in the city or urban environments and we're curious.

Re: Modern city dwellers have lost about half their gut microbes

#17
post #8

"Moeller and others also suggest identifying the missing microbes may be the first step toward bringing them back. “If we determine that these groups were providing important functions to keep humans healthy,” Maccaro says, “perhaps we can restore them with probiotics.” Oh really? Nice submarine for Actimel, Yakult etc.

Unfortunately, the most effective treatment I know of to change gut biome is bacteriotherapy via a method many people find off-putting and violating.

I think, for the time being, people are much more likely to accept a probiotic.

Re: Modern city dwellers have lost about half their gut microbes

#18
post #8

"Moeller and others also suggest identifying the missing microbes may be the first step toward bringing them back. “If we determine that these groups were providing important functions to keep humans healthy,” Maccaro says, “perhaps we can restore them with probiotics.” Oh really? Nice submarine for Actimel, Yakult etc.

Well, it's either a pill, or moving out of the city, or a fecal transplant (assuming that the urban / rural divide is relevant, and not just a proxy for diet).

I don't live in the city, but if I were told that I would be healthier with more of these microbes that my environment doesn't support, I'd opt for the pill.

Re: Modern city dwellers have lost about half their gut microbes

#19
post #3
post #2

Could this explain trends like increasing food allergies in countries where more and more people are becoming urban dwellers?

It's not impossible, and it might even be plausible... But it's a really, really difficult question. People outside of science: don't make the mistake of thinking that scientists haven't thought about this before! haha

What is that supposed to mean?

Re: Modern city dwellers have lost about half their gut microbes

#20
Does anyone know of probiotics with a variety of bacteria? Currently they (and yoghurts) seem to be just a single type, which doesn't make a lot of sense to me. If there are unusual bacteria out there where do they come from and how can we get them?

I've done a bunch of anti-biotics in the last few years so what to get back to what I was.

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