At the same time, it may become more relevant in the future (I'm thinking along the lines of 3-10 years out, probably not any time too soon with current market conditions). In that case, my skills may be incredibly valuable.
Until recently I've mainly been doing React+node+Typescript dev and system administration+AWS management anyway, all of which are skills that translate well to any other domain. Recently I've been doing some web3 stuff (which is completely new to me), so that's an area where I especially worry the skills I'm developing could become irrelevant.
But I don't think/hope they will. Even if they do, I have all the other skills to "fall back on" and as with any niche skill you develop, you have to consider its future value. For web3 development, I think if it has any value in the future, it will have a lot of value, so I'm happy with this time investment.
As for other considerations, I really like the company and people I work with. We provide financial services to other crypto companies (so we're essentially B2B). There is a ton of toxicity in the crypto industry unfortunately (Coinbase and Kraken are two prominent examples) so that's my biggest gripe with publicly identifying with "crypto values" (I'm pretty far from libertarian anyway). So my main concern really is people forming an opinion about how my values might align with their company values due to my work history.
But that could be said for working for any FAANG also (since they're all largely amoral, capitalistic, profit-drive companies)