Combining these two for any significant amount of time seems like a recipe for microbiota dysbiosis.
It would be interesting to somehow determine if most of the oxygen is absorbed in the small or large intestine.
Mucus is what keeps bacteria from reaching the intestinal epithelium, especially in the large intestine (https://www.pnas.org/doi/10.1073/pnas.0803124105), and oxygenating the gut will cause a bloom in facultative aneorobes including E. coli and Salmonella, while killing anaerobic commensals like Bacteroidetes.