Nothing any of us do today will exist in 500 years, but I suspect Beethoven's Ninth will continue to inspire.
Similarly, the 500th anniversary of Josquin des Prez, a much bigger star, was celebrated last year via numerous CD releases, journal papers, and concerts. Josquin is so famous that even though he may have been neglected for 100-200 years he may well be considered part of the enlarged classical canon today. In fact Robert Levin in a lecture explicitly mentioned Josquin when he asked the very same question about Beethoven. Going by these examples, it seems likely that Beethoven will endure.