Earlier quoted context omitted.
Benzo withdrawal can as well.
Oh, I didn't know.
And again, you get to that state in as little as a week.
Alcohol takes much longer.
Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
131–140 of 400 posts
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#132I took 1 benzodiazepine bill once about 15 years ago and I still remember the effect--instant total relaxation. I remember thinking that it felt too good and that it's something I shouldn't let myself have again. Hearing about its long term effects, I feel somewhat lucky.
When I am having a bad panic attack and take 1 Ativan, if I am lucky I go from being convinced I am dying to able to function with some difficulty. Lotsa brains, lots of different reactions to the drug.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#133Just came off benzos withdrawal those things are insanely horrible, delirium, depersonalization, derealization, muscle tremors, and persistent headaches were some of the symptoms I experienced. Thank God I did not have seizures.
take magnesium lthreonate for an effective synapse recovery
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#134Earlier quoted context omitted.
The reality is that many doctors these days will not prescribe large amounts of benzos, certainly not just willy nilly.
I'm not just talking about benzos, but also anti psychotics, amphetamines, statins, and basically the whole gamut. My brother is a pharmacist, and is constantly shocked by the prescriptions that healthy people bring in to get filled. The medical field has been unjustly given too much prestige.
If they're healthy, couldn't that be because of the medicine?
A lot of people have conditions that medicine treats so well you wouldn't even know they had a condition at all.
I know many people who have taken antipsychotics, amphetamines, and statins for decades and it was perfectly fine for them. I also personally know some judgmental pharmacists too. All I'll say is, there's a reason pharmacists and doctors are distinct professions.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#135I was prescribed benzos because of sleeping issues, but I was also taking phenibut at the same time. After about 3 weeks of using large doses of the benzos every night, I stopped taking them, but a year later I still feel pangs of withdrawal sometimes when I get stressed. It took me another 4 months to get off the phenibut and a month or so after that before my sleep returned to normal. There were months where I mayb…
To anyone curious about phenibut: Don't. Just don't. Please. Just a few weeks of usage can cause dependence. It is notorious for causing compulsive redosing. Withdrawal can make you unable to sleep for days, with lingering effects like panic attacks and anhedonia for weeks and weeks. Withdrawal from larger quantities can cause auditory and visual hallucinations and seizures and can even KILL you. Avoiding serious sym…
Well that's frightening. I tried it out recently and didn't really feel anything that would get me hooked on it but maybe that's naive.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#136Why there aren't more studies on humans? It's not difficult to find people who have been taking benzos or other related drugs for years.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#137Daily use of benzos is extremely bad in general - the physical addiction is not pleasant to withdraw from, and it significantly increases the risk of dementia in old age.
> dementia in old age. Spoke to a psychiatrist on this one. He was saying The Lancet longitudinal study was bunk and that Xanax use was not one of concern. I'm not saying he's correct, but he literally laughed at my objection to Xanax, including it's now very long history of use with an average dose of 6mg/day.
doctors often laugh at their own ignorance and pride
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#138Earlier quoted context omitted.
Doctors prescribe benzos for sleep issues and tell you they are safe? Do you live in the US?
Yes. Some doctors do; some don't. My new doctor was horrified when I told her what I was prescribed. She's young, and she said the first thing they say in medical school nowadays is, "Benzos are bad." My first doctor was much older and clearly from a different era of medical school.
My doctor is young and gave me a limited prescription for ten doses of lorazepam while I was adjusting to duloxetine, which often exacerbates anxiety in the first couple weeks. I was experiencing regular panic attacks before starting so he wanted to be sure they didn't become disabling. Benzos are safe when the amount and duration are carefully controlled. The problem is chronic usage, which is more or less contraindicated these days.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#139xan not workib
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#140Benzos are pretty terrible drugs in general. The physical addiction potential and withdrawal people are going through are enough to dissuade me from touching them. For folks dealing with anxiety, I recommend trying propranolol. It is not as powerful, but sometimes it is enough to achieve the desired effect and the side effects are way less severe.
I take a benzo ICE as needed, but was on them for a while and never really noticed degenerative affects though I’m young though. Should I be worried?
From the article:
> When diazepam medication was stopped, the effects lingered for a while but were eventually reversed.
I think you’ll be okay.