It is so frustrating that the end result is years away. I hope that they don’t just look for some equivalent micro drug but perform experiments with the actual growth factor in human test subjects.
Transfusion of brain fluid from young mice improves memory in old mice
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Re: Transfusion of brain fluid from young mice improves memory in old mice
#12Don't let the oligarchs here about this.
This makes me wonder about transmission of diseases such as prions in that kind of transfusion though. Perhaps better to understand the fundamental process and synthesize the core chemicals involved (if it comes to that).
Re: Transfusion of brain fluid from young mice improves memory in old mice
#13Haven't similar things been observed with blood transfusions of young blood into the elderly, which was then found to actually be unnecessary - even just diluting the blood with something neutral and clean produced similar results.
"The solution to pollution is dilution"
Re: Transfusion of brain fluid from young mice improves memory in old mice
#14this above article is kind of inflammatory, however, this paper is incredibly interesting. I read it this morning and the concept of changing CSF in order to have an increase in oligodendrocyte progenitor cell proliferation and differentiation is such a creative idea; a lot of the idea has focused on increasing flow in order to move waste, etc with csf. I think this concept that CSF is also acting as an important mec…
I'm curious, what is your favorite paper of all time (the specification of 'last five years' sounds like it's not this one?)
Re: Transfusion of brain fluid from young mice improves memory in old mice
#15Haven't similar things been observed with blood transfusions of young blood into the elderly, which was then found to actually be unnecessary - even just diluting the blood with something neutral and clean produced similar results. "The solution to pollution is dilution"
Could it be this simple? Shit just builds up in the blood that the liver and kidneys and stuff are not 100% efficient at removing? So you just need to... get rid of it or dilute it?
I mean that can't possibly be a full solution but could a major "win" on life span or at least health span be as simple as some kind of dialysis session?
Could this also be a hidden mechanism involved in some of that hyperbaric oxygen chamber evidence for life/health extension? Maybe all that oxygen oxidizes and destroys some of this stuff.
Re: Transfusion of brain fluid from young mice improves memory in old mice
#16Haven't similar things been observed with blood transfusions of young blood into the elderly, which was then found to actually be unnecessary - even just diluting the blood with something neutral and clean produced similar results. "The solution to pollution is dilution"
So drinking more water would be enough?
Re: Transfusion of brain fluid from young mice improves memory in old mice
#17I wonder how long until this is a thing some people do; like the blood transfusions from younger/healthy people.
Russell manages to give a laugh at even the most disturbing topics. Here is is his show about the huge industry of blood extraction. https://youtu.be/82pOL361zUk
Re: Transfusion of brain fluid from young mice improves memory in old mice
#18The mice boomers will never relinquish their power now.
Re: Transfusion of brain fluid from young mice improves memory in old mice
#19Haven't similar things been observed with blood transfusions of young blood into the elderly, which was then found to actually be unnecessary - even just diluting the blood with something neutral and clean produced similar results. "The solution to pollution is dilution"
So drinking more water would be enough?
This isn't my area of expertise at all.
A personal experience that comes to mind is when my childhood cat developed kidney disease.
She drank plenty of water, urinated excessively, and her blood still became toxic without regular (~daily) intervention in the form of adding saline to her blood intravenously. Like a light switch she'd resume normal life after the saline bag emptied into her blood, then slowly become ill again in the next 24-48hrs.
Re: Transfusion of brain fluid from young mice improves memory in old mice
#20Earlier quoted context omitted.
So drinking more water would be enough?
This isn't my area of expertise at all. A personal experience that comes to mind is when my childhood cat developed kidney disease. She drank plenty of water, urinated excessively, and her blood still became toxic without regular (~daily) intervention in the form of adding saline to her blood intravenously. Like a light switch she'd resume normal life after the saline bag emptied into her blood, then slowly become il…
You must have loved that cat very much.