Is 60mg a typical dose of fexofenadine? I'm only familiar with it as 180mg tablets (I was initially prescribed 180mg twice daily for dermatographic urticaria, and currently take 360mg twice daily).
Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
31–40 of 65 posts
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#32Earlier quoted context omitted.
> hit and run is a victimless crime Not clear on your logic. A hit and run has a victim: whoever is the owner of the person or property you damaged. In contrast, a drunk driver who is not under excess influence of the alcohol in his system and who gets from point A to point B safely, has victimized no one.
>In contrast, drunk driver who is not under excess influence of the alcohol in his system and who gets from point A to point B safely, has created no victims. And what of the drunk driver under excess influence who creates a victim?
presumably he is still subject to the laws that relate to creating a victim
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#33Earlier quoted context omitted.
It seems like a "victimless crime" in the same way that a hit and run is a victimless crime, as long as you get away with it. Someone has willfully chosen to make life more dangerous for everyone else. It's possible they won't be caught, but ignoring the act carries a real possibility of harm. There are people who would drive drunk every single day, if they could get away with it.
The founder of madd in america thinks they went too far though. https://www.washingtontimes.com/news/2002/aug/6/20020806-035... > Candy Lightner, MADD’s founder, says she disassociated herself from the movement in 1985 because she believed the organization was headed in the wrong direction. > “It has become far more neo-prohibitionist than I had ever wanted or envisioned,” said Mrs. Lightner, who founded MADD after h…
I would sooner drive after a couple beers with dinner than after taking Benadryl (diphenhydramine). That’s not because I think alcohol is safe to drive on.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#34To play devil’s advocate: People forget that drunk driving laws started as the result of activist campaigns from special interest groups only a few decades ago. It is itself a victimless crime; we have existing laws against reckless driving, causing accidents, vehicular manslaughter, etc.; and as this study shows there are plenty of common, less regulated (i.e. showing no signs of impairment yet blowing into a measur…
Shooting a gun into a crowd and not hitting anyone is also a "victimless crime", that doesn't mean it isn't high risk behavior that should be discouraged. The reality is that the large majority of drunk drivers are chronic drunks and drunk driving rules are pretty effective at taking them off the road.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#35To play devil’s advocate: People forget that drunk driving laws started as the result of activist campaigns from special interest groups only a few decades ago. It is itself a victimless crime; we have existing laws against reckless driving, causing accidents, vehicular manslaughter, etc.; and as this study shows there are plenty of common, less regulated (i.e. showing no signs of impairment yet blowing into a measur…
Shooting a gun into a crowd and not hitting anyone is also a "victimless crime", that doesn't mean it isn't high risk behavior that should be discouraged. The reality is that the large majority of drunk drivers are chronic drunks and drunk driving rules are pretty effective at taking them off the road.
>the large majority of drunk drivers are chronic drunks and drunk driving rules are pretty effective at taking them off the road.
That's a good point. Aren't you now arguing though that the vast majority of drinkers, who are not chronic drunks, be punished for the actions of a few?
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#36To play devil’s advocate: People forget that drunk driving laws started as the result of activist campaigns from special interest groups only a few decades ago. It is itself a victimless crime; we have existing laws against reckless driving, causing accidents, vehicular manslaughter, etc.; and as this study shows there are plenty of common, less regulated (i.e. showing no signs of impairment yet blowing into a measur…
WTF, it's not a victimless crime. You have a much higher chance of getting in an accident and killing someone when you're drunk. Someone dies every 50 minutes in America from drunk driving accidents.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#372nd gen antihistamines (Fexofenadine, Cetirizine, Loratidine) are definitely what you want for allergies. 1st gen like Benadryl/Diphenydramine have awful side effects. I highly recommend nasal sprays like Fluticasone as well, available OTC in the US these days and amazing stuff.
I would argue that, whatever “generation” it is, cetirizine does not deserve credit for being second generation. I know plenty of people with extremely obvious CNS effects from it. In contrast, loratadine seems innocuous.
Cetirizine is a "no go" for pilots. Fexofenadine and loratadine are OK to fly on though, as is fluticasone.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#38Earlier quoted context omitted.
> Fluticasone A corticosteroid, it has awful side effects as well
Maybe. But I would say for me the benefits of not suffering "breakthrough" hayfever attacks far outweigh the side effects. Antihistamines are great - but the nasal corticosteroids are what really control my hayfever (1) when used consistently. 1 - Hayfever so bad that I used to have to get custom serum shots containing the local pollen profile, every 2 weeks as a kid. Had anaphylaxis twice.
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Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#392nd gen antihistamines (Fexofenadine, Cetirizine, Loratidine) are definitely what you want for allergies. 1st gen like Benadryl/Diphenydramine have awful side effects. I highly recommend nasal sprays like Fluticasone as well, available OTC in the US these days and amazing stuff.
Ironically, whilst having terrible hayfever... Not taking Antihistamines at all seems to have had the most profound effect on me between the gen 1 and 2 meds. If I didn't know any better, I would almost figure I was having some sort of rebound effect from taking them in the first place. Which is odd, because I have been diagnosed with having Allergic Sinusitis, which triggers an inflammatory asthma if not careful.
I used 1st gen stuff like Chlorpheniramine and Diphenhydramine to start. Tried some second gen stuff not too long ago, and it worked pretty well too; but not as well just not taking any? It's weird. Meanwhile if I have an actual allergy attack, I keep Benadryl around for just in case. Because again, not taking any of these seems to just leave me without any allergies now? Or as bad at least. But Benadryl seems to still have some effect, where as I need a couple days of taking the 2nd gen stuff to actually get any effect; if any at all.
All in all, I'm confused now as to which I should even take considering everything in how my reactions have been to it all. So I just don't take any unless things are real bad now. Which they usually aren't.
Maybe I outgrew my allergies? I doubt it, cause I still sneeze around cats and stuff. heh.
Re: Effects of fexofenadine, diphenhydramine, and alcohol on driving performance
#40The article is extremely short, but comparing 2-4 OTC doses of diphenhydramine to a level of alcohol concentration above what constitutes a DUI in most places seems like an odd choice? Or is that just a matter of proof of concept, go for the big obvious demonstration first?
2 doses of diphenhydramine can have very noticeable and profound effects on many people, 50mg total isn't a light dose by any metric. That seems fine as a comparison to 0.1% BAC. But 60mg Fexofenadine makes no sense to me in comparison. It's usually 180mg in a single pill.
Hate to break it to you, but 50mg is pretty much a common dosage for most people taking Diphen. At least where I lived over the past few decades... This is mostly due to the effect of 'if 1 pill is almost enough to do the job, then 2 pills should be adequate'. You see this a lot with people who take Tylenol and/or Advil. Tylenol overdoses are more common because of the frequency of acetaminophens use in other medications in combination with people taking Tylenol not realizing they are doubling/tripling their doses.
So having people end up driving on 50mg+ doses of the dryl is not uncommon in places like Canada. Pair it with a dose or two of pseudoephidrine hydrochloride as well, and you basically have a breath easy cocktail that might put you to sleep, or might keep you awake all night.